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Changing trends of contact allergens in Thailand : A 12-year retrospective study

Sukakul, Thanisorn LU orcid ; Chaweekulrat, Pichanee ; Limphoka, Pichaya and Boonchai, Waranya (2019) In Contact Dermatitis 81(2). p.124-129
Abstract

BACKGROUND: Contact allergen prevalences often change. Continual surveillance is necessary to detect trends in sensitization rates and emerging allergens.

OBJECTIVE: To identify the prevalence of, and trends in, the positive reactions to each allergen in the baseline series during a 12-year period in Thailand.

METHODS: The medical records of 2803 patients who underwent patch testing at the Contact Dermatitis Clinic, Siriraj Hospital, between 2006 and 2018, were retrospectively reviewed. The baseline series used by the clinic was adapted from the European and the International baseline series. The patch testing results were subdivided into 2-year blocks in order to compare the prevalences of each allergen.

RESULTS: The... (More)

BACKGROUND: Contact allergen prevalences often change. Continual surveillance is necessary to detect trends in sensitization rates and emerging allergens.

OBJECTIVE: To identify the prevalence of, and trends in, the positive reactions to each allergen in the baseline series during a 12-year period in Thailand.

METHODS: The medical records of 2803 patients who underwent patch testing at the Contact Dermatitis Clinic, Siriraj Hospital, between 2006 and 2018, were retrospectively reviewed. The baseline series used by the clinic was adapted from the European and the International baseline series. The patch testing results were subdivided into 2-year blocks in order to compare the prevalences of each allergen.

RESULTS: The prevalences of positive reactions to nickel, fragrance mixes I and II, dichromate, cobalt, carba mix, methyldibromo glutaronitrile, paraben mix, neomycin sulfate, methylisothiazolinone (MI), epoxy resin, N-isopropyl-N-phenyl-4-phenylenediamine and the corticosteroids significantly decreased. Methylchloroisothiazolinone (MCI)/MI was the only allergen associated with a significant increase of positive reactions, from 2.4% to 10.7%. However, the proportion of positive reactions to MCI/MI decreased in the final 2-year period.

CONCLUSIONS: Approximately half of the substances in the screening patch test series showed a decline in the number of positive reactions, whereas MCI/MI showed an increasing prevalence.

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author
; ; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Allergens, Dermatitis, Allergic Contact/diagnosis, Female, Humans, Male, Middle Aged, Patch Tests, Prevalence, Retrospective Studies, Thailand/epidemiology
in
Contact Dermatitis
volume
81
issue
2
pages
6 pages
publisher
Wiley-Blackwell
external identifiers
  • pmid:30977136
  • scopus:85066889804
ISSN
0105-1873
DOI
10.1111/cod.13289
language
English
LU publication?
no
id
26406cd9-3f20-4ddc-b0c8-b7d14b34ec00
date added to LUP
2021-04-12 13:06:35
date last changed
2024-05-04 05:40:30
@article{26406cd9-3f20-4ddc-b0c8-b7d14b34ec00,
  abstract     = {{<p>BACKGROUND: Contact allergen prevalences often change. Continual surveillance is necessary to detect trends in sensitization rates and emerging allergens.</p><p>OBJECTIVE: To identify the prevalence of, and trends in, the positive reactions to each allergen in the baseline series during a 12-year period in Thailand.</p><p>METHODS: The medical records of 2803 patients who underwent patch testing at the Contact Dermatitis Clinic, Siriraj Hospital, between 2006 and 2018, were retrospectively reviewed. The baseline series used by the clinic was adapted from the European and the International baseline series. The patch testing results were subdivided into 2-year blocks in order to compare the prevalences of each allergen.</p><p>RESULTS: The prevalences of positive reactions to nickel, fragrance mixes I and II, dichromate, cobalt, carba mix, methyldibromo glutaronitrile, paraben mix, neomycin sulfate, methylisothiazolinone (MI), epoxy resin, N-isopropyl-N-phenyl-4-phenylenediamine and the corticosteroids significantly decreased. Methylchloroisothiazolinone (MCI)/MI was the only allergen associated with a significant increase of positive reactions, from 2.4% to 10.7%. However, the proportion of positive reactions to MCI/MI decreased in the final 2-year period.</p><p>CONCLUSIONS: Approximately half of the substances in the screening patch test series showed a decline in the number of positive reactions, whereas MCI/MI showed an increasing prevalence.</p>}},
  author       = {{Sukakul, Thanisorn and Chaweekulrat, Pichanee and Limphoka, Pichaya and Boonchai, Waranya}},
  issn         = {{0105-1873}},
  keywords     = {{Adult; Allergens; Dermatitis, Allergic Contact/diagnosis; Female; Humans; Male; Middle Aged; Patch Tests; Prevalence; Retrospective Studies; Thailand/epidemiology}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{124--129}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Contact Dermatitis}},
  title        = {{Changing trends of contact allergens in Thailand : A 12-year retrospective study}},
  url          = {{http://dx.doi.org/10.1111/cod.13289}},
  doi          = {{10.1111/cod.13289}},
  volume       = {{81}},
  year         = {{2019}},
}