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A new liposomal contrast medium for CT of the liver. An imaging study in a rabbit tumour model

Leander, Peter LU (1996) In Acta Radiologica 37(1). p.63-68
Abstract
A new type of liposomal liver-specific contrast medium was studied in an experimental tumour model. Rabbits were inoculated with VX2-carcinoma directly in the liver of laparotomy. CT studies were carried out 14 days after inoculation. The liver-specific contrast medium consisted of a suspension of liposomes in a 100 mg I/ml iodixanol solution, with equal amounts of encapsulated and nonencapsulated iodixanol. It was administered at a dose of 200 mg I/kg. The contrast of normal liver tissue to tumorous tissue was significantly increased by contrast medium administration, the increase being largest 10 min after injection.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Radiologica
volume
37
issue
1
pages
63 - 68
publisher
SAGE Publications
external identifiers
  • pmid:8611327
  • scopus:0029685559
ISSN
1600-0455
language
English
LU publication?
yes
id
264b8f0a-79cc-4d80-b832-9e8f47816530 (old id 1110569)
date added to LUP
2016-04-01 17:02:16
date last changed
2022-01-28 23:55:35
@article{264b8f0a-79cc-4d80-b832-9e8f47816530,
  abstract     = {{A new type of liposomal liver-specific contrast medium was studied in an experimental tumour model. Rabbits were inoculated with VX2-carcinoma directly in the liver of laparotomy. CT studies were carried out 14 days after inoculation. The liver-specific contrast medium consisted of a suspension of liposomes in a 100 mg I/ml iodixanol solution, with equal amounts of encapsulated and nonencapsulated iodixanol. It was administered at a dose of 200 mg I/kg. The contrast of normal liver tissue to tumorous tissue was significantly increased by contrast medium administration, the increase being largest 10 min after injection.}},
  author       = {{Leander, Peter}},
  issn         = {{1600-0455}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{63--68}},
  publisher    = {{SAGE Publications}},
  series       = {{Acta Radiologica}},
  title        = {{A new liposomal contrast medium for CT of the liver. An imaging study in a rabbit tumour model}},
  volume       = {{37}},
  year         = {{1996}},
}