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Eye evolution: a question of genetic promiscuity

Nilsson, Dan-E LU (2004) In Current Opinion in Neurobiology 14(4). p.407-414
Abstract
Animal eyes have long served as a classical example of independent origin followed by convergence of structures onto a few different solutions. During the past decade this view has been challenged by the discovery of shared developmental regulatory genes. The Pax6 gene in particular is almost universally employed for eye formation in bilaterian animals, despite widely different embryological origins. The resulting controversy on the multiple or single origins of animal eyes has gradually been sharpened by continuing discoveries of further general similarities in the genetic regulatory circuits of eye development. Recent work on gene expression in specified cell types, together with comparative studies of developmental genes in cnidarians,... (More)
Animal eyes have long served as a classical example of independent origin followed by convergence of structures onto a few different solutions. During the past decade this view has been challenged by the discovery of shared developmental regulatory genes. The Pax6 gene in particular is almost universally employed for eye formation in bilaterian animals, despite widely different embryological origins. The resulting controversy on the multiple or single origins of animal eyes has gradually been sharpened by continuing discoveries of further general similarities in the genetic regulatory circuits of eye development. Recent work on gene expression in specified cell types, together with comparative studies of developmental genes in cnidarians, now show some promise to a solution of the controversy. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Current Opinion in Neurobiology
volume
14
issue
4
pages
407 - 414
publisher
Elsevier
external identifiers
  • pmid:15321060
  • wos:000223593100002
  • scopus:4043129557
ISSN
1873-6882
DOI
10.1016/j.conb.2004.07.004
language
English
LU publication?
yes
id
b0715610-64aa-4b41-b2d1-a48de4e755ee (old id 268695)
date added to LUP
2007-10-29 09:16:38
date last changed
2017-01-01 04:54:00
@article{b0715610-64aa-4b41-b2d1-a48de4e755ee,
  abstract     = {Animal eyes have long served as a classical example of independent origin followed by convergence of structures onto a few different solutions. During the past decade this view has been challenged by the discovery of shared developmental regulatory genes. The Pax6 gene in particular is almost universally employed for eye formation in bilaterian animals, despite widely different embryological origins. The resulting controversy on the multiple or single origins of animal eyes has gradually been sharpened by continuing discoveries of further general similarities in the genetic regulatory circuits of eye development. Recent work on gene expression in specified cell types, together with comparative studies of developmental genes in cnidarians, now show some promise to a solution of the controversy.},
  author       = {Nilsson, Dan-E},
  issn         = {1873-6882},
  language     = {eng},
  number       = {4},
  pages        = {407--414},
  publisher    = {Elsevier},
  series       = {Current Opinion in Neurobiology},
  title        = {Eye evolution: a question of genetic promiscuity},
  url          = {http://dx.doi.org/10.1016/j.conb.2004.07.004},
  volume       = {14},
  year         = {2004},
}