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Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania : A community-based cross-sectional study

Mtei, Monica ; Mboya, Innocent B LU orcid ; Mgongo, Melina ; Manongi, Rachel ; Amour, Caroline ; Bilakwate, Julieth S ; Nyaki, Ahmed Y ; Ngocho, James ; Jonas, Norman and Farah, Amina , et al. (2023) In Human Vaccines & Immunotherapeutics 19(1). p.1-8
Abstract

COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines has been one of the factors leading to hesitancy. We aimed to assess the COVID-19 vaccine confidence (safety and effectiveness), associated factors, and its effects on vaccine uptake among general community members in Tanzania. This was a community-based cross-sectional survey conducted from December 2021 to April 2022 in six regions of Tanzania mainland and two regions in Zanzibar. Participants were interviewed using an electronic questionnaire. Multiple logistic regression models... (More)

COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines has been one of the factors leading to hesitancy. We aimed to assess the COVID-19 vaccine confidence (safety and effectiveness), associated factors, and its effects on vaccine uptake among general community members in Tanzania. This was a community-based cross-sectional survey conducted from December 2021 to April 2022 in six regions of Tanzania mainland and two regions in Zanzibar. Participants were interviewed using an electronic questionnaire. Multiple logistic regression models estimated odds ratios (ORs) and 95% confidence interval (CI) for factors associated with vaccine confidence. All analyses were performed using SPSS version 25.0. The study enrolled 3470 general Tanzanian community members; their mean age was 40.3 (standard deviation ±14.9) years, and 34% were males. The proportion of COVID-19 vaccine confidence was 54.6%. Geographical region, residence area, COVID-19 disease risk perception, and good knowledge of COVID-19 vaccines were significantly associated with COVID-19 vaccine confidence. Confidence in COVID-19 vaccines was associated with over three times higher odds of vaccine uptake. Confidence in COVID-19 vaccines was low in Tanzania. Innovative community engagement strategies and region-specific interventions are needed to improve comprehensive knowledge and address community perceptions and attitudes toward COVID-19 vaccines.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Human Vaccines & Immunotherapeutics
volume
19
issue
1
article number
2191576
pages
1 - 8
publisher
Taylor & Francis
external identifiers
  • scopus:85151956777
  • pmid:37017234
ISSN
2164-5515
DOI
10.1080/21645515.2023.2191576
language
English
LU publication?
yes
id
270925da-9137-4b96-84d5-ff0824d78025
date added to LUP
2023-04-07 10:45:59
date last changed
2024-04-19 21:40:56
@article{270925da-9137-4b96-84d5-ff0824d78025,
  abstract     = {{<p>COVID-19 is a major public health threat associated with increased disease burden, mortality, and economic loss to countries and communities. Safe and efficacious COVID-19 vaccines are key in halting and reversing the pandemic. Low confidence in vaccines has been one of the factors leading to hesitancy. We aimed to assess the COVID-19 vaccine confidence (safety and effectiveness), associated factors, and its effects on vaccine uptake among general community members in Tanzania. This was a community-based cross-sectional survey conducted from December 2021 to April 2022 in six regions of Tanzania mainland and two regions in Zanzibar. Participants were interviewed using an electronic questionnaire. Multiple logistic regression models estimated odds ratios (ORs) and 95% confidence interval (CI) for factors associated with vaccine confidence. All analyses were performed using SPSS version 25.0. The study enrolled 3470 general Tanzanian community members; their mean age was 40.3 (standard deviation ±14.9) years, and 34% were males. The proportion of COVID-19 vaccine confidence was 54.6%. Geographical region, residence area, COVID-19 disease risk perception, and good knowledge of COVID-19 vaccines were significantly associated with COVID-19 vaccine confidence. Confidence in COVID-19 vaccines was associated with over three times higher odds of vaccine uptake. Confidence in COVID-19 vaccines was low in Tanzania. Innovative community engagement strategies and region-specific interventions are needed to improve comprehensive knowledge and address community perceptions and attitudes toward COVID-19 vaccines.</p>}},
  author       = {{Mtei, Monica and Mboya, Innocent B and Mgongo, Melina and Manongi, Rachel and Amour, Caroline and Bilakwate, Julieth S and Nyaki, Ahmed Y and Ngocho, James and Jonas, Norman and Farah, Amina and Amour, Maryam and Kalolo, Albino and Kengia, James T and Tinuga, Florian and Ngalesoni, Frida and Bakari, Abdalla H and Kirakoya, Fatimata B and Araya, Awet and Kapologwe, Ntuli A and Msuya, Sia E}},
  issn         = {{2164-5515}},
  language     = {{eng}},
  month        = {{04}},
  number       = {{1}},
  pages        = {{1--8}},
  publisher    = {{Taylor & Francis}},
  series       = {{Human Vaccines & Immunotherapeutics}},
  title        = {{Confidence in COVID-19 vaccine effectiveness and safety and its effect on vaccine uptake in Tanzania : A community-based cross-sectional study}},
  url          = {{http://dx.doi.org/10.1080/21645515.2023.2191576}},
  doi          = {{10.1080/21645515.2023.2191576}},
  volume       = {{19}},
  year         = {{2023}},
}