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Histologic reactions to particulate wear debris in different mesenchymal tissues - Studies on the nonreplaced compartment from revised uni-knees

Hansson, Ulrik LU ; Blunn, G and Ryd, L (2004) In Journal of Arthroplasty 19(4). p.481-487
Abstract
The interface between bone and artificial-joint implants consists of soft tissue. This tissue varies from fibrocartilage to loose fibrous tissue. Tissues that resemble those can be found in normal joints. Sixteen knees with unicompartmental knee prostheses, revised because of excessive wear of the tibial insert, were studied. Synovium, synovial fluid, cartilage, and bone from the nonreplaced compartment were Studied with light microscopy. We found wear particles and reactions to those in all tissues except cartilage. In the subchondral bone, we found osteolytic-like processes undermining the cartilage peripherally. Our conclusion from these findings is that the histologic composition of the bone-implant interface might be an important... (More)
The interface between bone and artificial-joint implants consists of soft tissue. This tissue varies from fibrocartilage to loose fibrous tissue. Tissues that resemble those can be found in normal joints. Sixteen knees with unicompartmental knee prostheses, revised because of excessive wear of the tibial insert, were studied. Synovium, synovial fluid, cartilage, and bone from the nonreplaced compartment were Studied with light microscopy. We found wear particles and reactions to those in all tissues except cartilage. In the subchondral bone, we found osteolytic-like processes undermining the cartilage peripherally. Our conclusion from these findings is that the histologic composition of the bone-implant interface might be an important factor regarding the reaction of the tissue to wear particles and, thus, component fixation. (C) 2004 Elsevier Inc. All rights reserved. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
histology, joint prosthesis, retrieval, wear particles
in
Journal of Arthroplasty
volume
19
issue
4
pages
481 - 487
publisher
Elsevier
external identifiers
  • pmid:15188108
  • wos:000222216500012
  • scopus:2642534348
ISSN
0883-5403
DOI
10.1016/j.arth.2003.11.013
language
English
LU publication?
yes
id
6d09e958-e961-40fd-bad0-2fe5515e580c (old id 273917)
date added to LUP
2007-10-29 14:16:22
date last changed
2017-01-01 04:55:05
@article{6d09e958-e961-40fd-bad0-2fe5515e580c,
  abstract     = {The interface between bone and artificial-joint implants consists of soft tissue. This tissue varies from fibrocartilage to loose fibrous tissue. Tissues that resemble those can be found in normal joints. Sixteen knees with unicompartmental knee prostheses, revised because of excessive wear of the tibial insert, were studied. Synovium, synovial fluid, cartilage, and bone from the nonreplaced compartment were Studied with light microscopy. We found wear particles and reactions to those in all tissues except cartilage. In the subchondral bone, we found osteolytic-like processes undermining the cartilage peripherally. Our conclusion from these findings is that the histologic composition of the bone-implant interface might be an important factor regarding the reaction of the tissue to wear particles and, thus, component fixation. (C) 2004 Elsevier Inc. All rights reserved.},
  author       = {Hansson, Ulrik and Blunn, G and Ryd, L},
  issn         = {0883-5403},
  keyword      = {histology,joint prosthesis,retrieval,wear particles},
  language     = {eng},
  number       = {4},
  pages        = {481--487},
  publisher    = {Elsevier},
  series       = {Journal of Arthroplasty},
  title        = {Histologic reactions to particulate wear debris in different mesenchymal tissues - Studies on the nonreplaced compartment from revised uni-knees},
  url          = {http://dx.doi.org/10.1016/j.arth.2003.11.013},
  volume       = {19},
  year         = {2004},
}