Investigation of Burkholderia cepacia nosocomial outbreak with high fatality in patients suffering from diseases other than cystic fibrosis
(2004) In Scandinavian Journal of Infectious Diseases 36(3). p.174-178- Abstract
- Over a 1-y period, 26 inpatients at the Jordan University Hospital in Amman were detected with bacteraemia (23 cases) or respiratory tract colonized with B. cepacia (3 cases). A combination of genetic identification and molecular typing has proved that all cases were caused by a single epidemic strain of B. cepacia genomovar IIIa. Nosocomial infections could be documented in 21/26 (81%) patients, mostly with severe underlying or malignant diseases other than cystic fibrosis, but the source of infection was undetected. The overall mortality related to infection with B. cepacia was 42%. All B. cepacia isolates were resistant to ampicillin, amikacin, carbenicillin and gentamicin; and mostly susceptible to piperacillin, chloramphenicol,... (More)
- Over a 1-y period, 26 inpatients at the Jordan University Hospital in Amman were detected with bacteraemia (23 cases) or respiratory tract colonized with B. cepacia (3 cases). A combination of genetic identification and molecular typing has proved that all cases were caused by a single epidemic strain of B. cepacia genomovar IIIa. Nosocomial infections could be documented in 21/26 (81%) patients, mostly with severe underlying or malignant diseases other than cystic fibrosis, but the source of infection was undetected. The overall mortality related to infection with B. cepacia was 42%. All B. cepacia isolates were resistant to ampicillin, amikacin, carbenicillin and gentamicin; and mostly susceptible to piperacillin, chloramphenicol, cotri-moxazole, tetracycline, ceftazidime, and tazocin (62-88%). This study demonstrates the nosocomial and high fatality of B. cepacia genomovar IIIa in Jordanian patients suffering from diseases other than cystic fibrosis. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/282019
- author
- Shehabi, AA ; Abu Al-Soud, Waleed LU ; Mahafzah, A ; Khuri-bulos, N ; Khader, IA ; Ouis, Ibn Sina LU and Wadström, Torkel LU
- organization
- publishing date
- 2004
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Scandinavian Journal of Infectious Diseases
- volume
- 36
- issue
- 3
- pages
- 174 - 178
- publisher
- Informa Healthcare
- external identifiers
-
- wos:000220616200002
- pmid:15119360
- scopus:2442630515
- ISSN
- 1651-1980
- DOI
- 10.1080/00365540410027166
- language
- English
- LU publication?
- yes
- id
- ff491e77-7111-48dd-a05a-def8e2d0e563 (old id 282019)
- date added to LUP
- 2016-04-01 16:24:52
- date last changed
- 2022-01-28 19:34:01
@article{ff491e77-7111-48dd-a05a-def8e2d0e563, abstract = {{Over a 1-y period, 26 inpatients at the Jordan University Hospital in Amman were detected with bacteraemia (23 cases) or respiratory tract colonized with B. cepacia (3 cases). A combination of genetic identification and molecular typing has proved that all cases were caused by a single epidemic strain of B. cepacia genomovar IIIa. Nosocomial infections could be documented in 21/26 (81%) patients, mostly with severe underlying or malignant diseases other than cystic fibrosis, but the source of infection was undetected. The overall mortality related to infection with B. cepacia was 42%. All B. cepacia isolates were resistant to ampicillin, amikacin, carbenicillin and gentamicin; and mostly susceptible to piperacillin, chloramphenicol, cotri-moxazole, tetracycline, ceftazidime, and tazocin (62-88%). This study demonstrates the nosocomial and high fatality of B. cepacia genomovar IIIa in Jordanian patients suffering from diseases other than cystic fibrosis.}}, author = {{Shehabi, AA and Abu Al-Soud, Waleed and Mahafzah, A and Khuri-bulos, N and Khader, IA and Ouis, Ibn Sina and Wadström, Torkel}}, issn = {{1651-1980}}, language = {{eng}}, number = {{3}}, pages = {{174--178}}, publisher = {{Informa Healthcare}}, series = {{Scandinavian Journal of Infectious Diseases}}, title = {{Investigation of Burkholderia cepacia nosocomial outbreak with high fatality in patients suffering from diseases other than cystic fibrosis}}, url = {{http://dx.doi.org/10.1080/00365540410027166}}, doi = {{10.1080/00365540410027166}}, volume = {{36}}, year = {{2004}}, }