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Electron Microscopy in Diagnostic Pathology with Reference to Mesenchymal Tumors

Carlén, Birgitta LU (1996)
Abstract
The experience acquired over a period of 15 years of diagnostic electron microscopy of fine needle aspirates and surgical specimens constitutes the base for this thesis. Some of the tumors analyzed represent rare soft tissue tumors, and consequently not very often ultrastructurally described. In locations where sarcomas are rare and unexpected, electron microscopy may contribute to a correct tumor classification when type specific structures are present.



Electron microscopic examination is a suitable method to confirm presence of mesenchymal tumor cells in cultures and to compare the morphology in cultures and fresh tumor tissue provided that the ultrastructural features are specific for the tumor in question.

... (More)
The experience acquired over a period of 15 years of diagnostic electron microscopy of fine needle aspirates and surgical specimens constitutes the base for this thesis. Some of the tumors analyzed represent rare soft tissue tumors, and consequently not very often ultrastructurally described. In locations where sarcomas are rare and unexpected, electron microscopy may contribute to a correct tumor classification when type specific structures are present.



Electron microscopic examination is a suitable method to confirm presence of mesenchymal tumor cells in cultures and to compare the morphology in cultures and fresh tumor tissue provided that the ultrastructural features are specific for the tumor in question.



Fine needle aspiration together with the use of electron microscopy is a reliable combination in the typediagnosis of small round cell malignant tumors of childhood and adolescence and spindle cell tumors as peripheral nerve sheath tumors, leiomyosarcoma and synovial sarcoma, especially of the monophasic variant.



Electron microscopy contributes to the understanding of successive morphologic changes in the dermal microvasculature of Kaposi´s sarcoma.



This thesis presents examples that highlight the value of electron microscopy in the multidisciplinary management of musculoskeletal tumors. (Less)
Please use this url to cite or link to this publication:
author
opponent
  • Dickersin, G Richard
organization
publishing date
type
Thesis
publication status
published
subject
keywords
synovial sarcoma, Kaposi´s sarcoma, epithelioid sarcoma, parachordoma, alveolar soft part sarcoma, small cell malignant tumors of childhood and adolescence, cultured cells, surgical specimens, Transmission electron microscopy, fine needle aspiration, General pathology, pathological anatomy, Patologi (allmän), patologisk anatomi
pages
32 pages
publisher
Department of Histopathology, University Hospital, Lund, Sweden.
defense location
Lund
defense date
1996-04-11 10:15
external identifiers
  • Other:ISRN-LUMEDW/MEPR-1015-SE
ISBN
91-628-1942-9
language
English
LU publication?
yes
id
c04cc841-e060-4c3d-811d-2db52e3aa2cb (old id 28256)
date added to LUP
2007-06-11 10:03:06
date last changed
2016-09-19 08:45:15
@phdthesis{c04cc841-e060-4c3d-811d-2db52e3aa2cb,
  abstract     = {The experience acquired over a period of 15 years of diagnostic electron microscopy of fine needle aspirates and surgical specimens constitutes the base for this thesis. Some of the tumors analyzed represent rare soft tissue tumors, and consequently not very often ultrastructurally described. In locations where sarcomas are rare and unexpected, electron microscopy may contribute to a correct tumor classification when type specific structures are present.<br/><br>
<br/><br>
Electron microscopic examination is a suitable method to confirm presence of mesenchymal tumor cells in cultures and to compare the morphology in cultures and fresh tumor tissue provided that the ultrastructural features are specific for the tumor in question.<br/><br>
<br/><br>
Fine needle aspiration together with the use of electron microscopy is a reliable combination in the typediagnosis of small round cell malignant tumors of childhood and adolescence and spindle cell tumors as peripheral nerve sheath tumors, leiomyosarcoma and synovial sarcoma, especially of the monophasic variant.<br/><br>
<br/><br>
Electron microscopy contributes to the understanding of successive morphologic changes in the dermal microvasculature of Kaposi´s sarcoma.<br/><br>
<br/><br>
This thesis presents examples that highlight the value of electron microscopy in the multidisciplinary management of musculoskeletal tumors.},
  author       = {Carlén, Birgitta},
  isbn         = {91-628-1942-9},
  keyword      = {synovial sarcoma,Kaposi´s sarcoma,epithelioid sarcoma,parachordoma,alveolar soft part sarcoma,small cell malignant tumors of childhood and adolescence,cultured cells,surgical specimens,Transmission electron microscopy,fine needle aspiration,General pathology,pathological anatomy,Patologi (allmän),patologisk anatomi},
  language     = {eng},
  pages        = {32},
  publisher    = {Department of Histopathology, University Hospital, Lund, Sweden.},
  school       = {Lund University},
  title        = {Electron Microscopy in Diagnostic Pathology with Reference to Mesenchymal Tumors},
  year         = {1996},
}