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Time course of ECG depolarization and repolarization changes during ischemia in PTCA recordings

Pueyo, E; Garcia, J; Wagner, G; Bailon, R; Sörnmo, Leif LU and Laguna, P (2004) In Methods of Information in Medicine 43(1). p.43-46
Abstract
Objectives: In this work we studied the temporal evolution of changes in the electrocardiogram (ECG) as a consequence of the induced ischemia during prolonged coronary angioplasty, comparing the time course of indexes reflecting depolarization and those reflecting repolarization. Methods: We considered both local (measured at specific points of the ECG) and global (obtained from the Karhunen-Loeve transform) indexes. In particular, the evolution of Q, R and S wave amplitudes during ischemia was analyzed with respect to classical indexes such as ST level. As a measurement of sensitivity we used an Ischemic Changes Sensor (ICS), which reflects the capacity of an index to detect changes in the ECG. Results: The results showed that, in leads... (More)
Objectives: In this work we studied the temporal evolution of changes in the electrocardiogram (ECG) as a consequence of the induced ischemia during prolonged coronary angioplasty, comparing the time course of indexes reflecting depolarization and those reflecting repolarization. Methods: We considered both local (measured at specific points of the ECG) and global (obtained from the Karhunen-Loeve transform) indexes. In particular, the evolution of Q, R and S wave amplitudes during ischemia was analyzed with respect to classical indexes such as ST level. As a measurement of sensitivity we used an Ischemic Changes Sensor (ICS), which reflects the capacity of an index to detect changes in the ECG. Results: The results showed that, in leads with low-amplitude ST-T complexes, the S wave amplitude was more sensitive in detecting ischemia than was the commonly used index ST60. It was found that in such leads the S wave amplitude initially exhibited a delayed response to ischemia when compared to ST60, but its performance was better from the second minute of occlusion. The global indexes describing the ST-T complex were, in terms of the ICS, superior to the S wave amplitude for ischemia detection. Conclusions: Ischemic ECG changes occur both at repolarization and depolarization, with alterations in the depolarization period appearing later in time. Local indexes are less sensitive to ischemia than global ones. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
QRS amplitudes, ischemia, angioplasty, ST value
in
Methods of Information in Medicine
volume
43
issue
1
pages
43 - 46
publisher
Schattauer
external identifiers
  • wos:000220474700011
  • pmid:15026835
  • scopus:1642306158
ISSN
0026-1270
language
English
LU publication?
yes
id
4dd4a198-504a-4c0b-a7f3-8713918f65a9 (old id 283577)
alternative location
http://www.schattauer.de/index.php?id=734&L=0&no_cache=1&artikel=511
date added to LUP
2007-10-30 07:45:52
date last changed
2017-01-15 04:15:49
@article{4dd4a198-504a-4c0b-a7f3-8713918f65a9,
  abstract     = {Objectives: In this work we studied the temporal evolution of changes in the electrocardiogram (ECG) as a consequence of the induced ischemia during prolonged coronary angioplasty, comparing the time course of indexes reflecting depolarization and those reflecting repolarization. Methods: We considered both local (measured at specific points of the ECG) and global (obtained from the Karhunen-Loeve transform) indexes. In particular, the evolution of Q, R and S wave amplitudes during ischemia was analyzed with respect to classical indexes such as ST level. As a measurement of sensitivity we used an Ischemic Changes Sensor (ICS), which reflects the capacity of an index to detect changes in the ECG. Results: The results showed that, in leads with low-amplitude ST-T complexes, the S wave amplitude was more sensitive in detecting ischemia than was the commonly used index ST60. It was found that in such leads the S wave amplitude initially exhibited a delayed response to ischemia when compared to ST60, but its performance was better from the second minute of occlusion. The global indexes describing the ST-T complex were, in terms of the ICS, superior to the S wave amplitude for ischemia detection. Conclusions: Ischemic ECG changes occur both at repolarization and depolarization, with alterations in the depolarization period appearing later in time. Local indexes are less sensitive to ischemia than global ones.},
  author       = {Pueyo, E and Garcia, J and Wagner, G and Bailon, R and Sörnmo, Leif and Laguna, P},
  issn         = {0026-1270},
  keyword      = {QRS amplitudes,ischemia,angioplasty,ST value},
  language     = {eng},
  number       = {1},
  pages        = {43--46},
  publisher    = {Schattauer},
  series       = {Methods of Information in Medicine},
  title        = {Time course of ECG depolarization and repolarization changes during ischemia in PTCA recordings},
  volume       = {43},
  year         = {2004},
}