Viewpoints in Clinical Proteomics - when will proteomics deliver clinically useful information?
(2012) In Proteomics Clinical Applications 6(7-8). p.343-345- Abstract
- Proteomics has not delivered biomarkers of clinical value, despite massive efforts. The technologies that are emerging today have, however, the power to reach deep into proteomes and to identify patterns associated with different diseases. The study design is then crucial and sample quality, bioinformatic approaches, pre-validation, using independent patient cohort, need to attract increased attention before proteomics will contribute to the needs of personalized medicine.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2859446
- author
- Borrebaeck, Carl LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- over-fitting, biobanks, pre-validation, bioinformatics, Signatures
- in
- Proteomics Clinical Applications
- volume
- 6
- issue
- 7-8
- pages
- 343 - 345
- publisher
- John Wiley & Sons Inc.
- external identifiers
-
- wos:000308093000003
- pmid:22696166
- scopus:84865587204
- ISSN
- 1862-8354
- DOI
- 10.1002/prca.201200020
- language
- English
- LU publication?
- yes
- id
- a92b2c3e-0c0a-46a4-b381-56bdb44d86fb (old id 2859446)
- date added to LUP
- 2016-04-01 10:46:48
- date last changed
- 2022-01-26 02:21:21
@article{a92b2c3e-0c0a-46a4-b381-56bdb44d86fb, abstract = {{Proteomics has not delivered biomarkers of clinical value, despite massive efforts. The technologies that are emerging today have, however, the power to reach deep into proteomes and to identify patterns associated with different diseases. The study design is then crucial and sample quality, bioinformatic approaches, pre-validation, using independent patient cohort, need to attract increased attention before proteomics will contribute to the needs of personalized medicine.}}, author = {{Borrebaeck, Carl}}, issn = {{1862-8354}}, keywords = {{over-fitting; biobanks; pre-validation; bioinformatics; Signatures}}, language = {{eng}}, number = {{7-8}}, pages = {{343--345}}, publisher = {{John Wiley & Sons Inc.}}, series = {{Proteomics Clinical Applications}}, title = {{Viewpoints in Clinical Proteomics - when will proteomics deliver clinically useful information?}}, url = {{http://dx.doi.org/10.1002/prca.201200020}}, doi = {{10.1002/prca.201200020}}, volume = {{6}}, year = {{2012}}, }