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Viewpoints in Clinical Proteomics - when will proteomics deliver clinically useful information?

Borrebaeck, Carl LU (2012) In Proteomics Clinical Applications 6(7-8). p.343-345
Abstract
Proteomics has not delivered biomarkers of clinical value, despite massive efforts. The technologies that are emerging today have, however, the power to reach deep into proteomes and to identify patterns associated with different diseases. The study design is then crucial and sample quality, bioinformatic approaches, pre-validation, using independent patient cohort, need to attract increased attention before proteomics will contribute to the needs of personalized medicine.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
over-fitting, biobanks, pre-validation, bioinformatics, Signatures
in
Proteomics Clinical Applications
volume
6
issue
7-8
pages
343 - 345
publisher
John Wiley & Sons
external identifiers
  • wos:000308093000003
  • pmid:22696166
  • scopus:84865587204
ISSN
1862-8354
DOI
10.1002/prca.201200020
language
English
LU publication?
yes
id
a92b2c3e-0c0a-46a4-b381-56bdb44d86fb (old id 2859446)
date added to LUP
2012-07-06 15:40:48
date last changed
2017-03-05 03:15:50
@article{a92b2c3e-0c0a-46a4-b381-56bdb44d86fb,
  abstract     = {Proteomics has not delivered biomarkers of clinical value, despite massive efforts. The technologies that are emerging today have, however, the power to reach deep into proteomes and to identify patterns associated with different diseases. The study design is then crucial and sample quality, bioinformatic approaches, pre-validation, using independent patient cohort, need to attract increased attention before proteomics will contribute to the needs of personalized medicine.},
  author       = {Borrebaeck, Carl},
  issn         = {1862-8354},
  keyword      = {over-fitting,biobanks,pre-validation,bioinformatics,Signatures},
  language     = {eng},
  number       = {7-8},
  pages        = {343--345},
  publisher    = {John Wiley & Sons},
  series       = {Proteomics Clinical Applications},
  title        = {Viewpoints in Clinical Proteomics - when will proteomics deliver clinically useful information?},
  url          = {http://dx.doi.org/10.1002/prca.201200020},
  volume       = {6},
  year         = {2012},
}