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Testicular cancer and occupational exposure to polyvinyl chloride plastics: A case-control study

Hardell, L; Malmqvist, N; Ohlson, CG; Westberg, H and Eriksson, Mikael LU (2004) In International Journal of Cancer 109(3). p.425-429
Abstract
Exposure to polyvinyl chloride. (PVC) plastics as a risk factor for testicular cancer was investigated. In total, 981 cases who were 20-75 years old and had reported to the Swedish Cancer Registry during 1993-1997 were included. One matched control from the population registry was used. Exposure was assessed by a questionnaire that was supplemented over the phone. Furthermore, an occupational hygienist qualified all exposures. In all, 791 matched pairs completed the questionnaire. Overall exposure to PVC plastics gave the odds ratio (OR)= 1.35, 95% confidence interval (Cl)= 1.06-1.71, increasing with > 10 year latency period to OR= 1.45, 95% Cl = 1.06-1.98. No dose-response relationships were found but rather an inverse relationship... (More)
Exposure to polyvinyl chloride. (PVC) plastics as a risk factor for testicular cancer was investigated. In total, 981 cases who were 20-75 years old and had reported to the Swedish Cancer Registry during 1993-1997 were included. One matched control from the population registry was used. Exposure was assessed by a questionnaire that was supplemented over the phone. Furthermore, an occupational hygienist qualified all exposures. In all, 791 matched pairs completed the questionnaire. Overall exposure to PVC plastics gave the odds ratio (OR)= 1.35, 95% confidence interval (Cl)= 1.06-1.71, increasing with > 10 year latency period to OR= 1.45, 95% Cl = 1.06-1.98. No dose-response relationships were found but rather an inverse relationship with the highest odds ratios in the lowest exposure category. In conclusion, no clear association with testicular cancer and exposure to PVC could be found in our study in contrast to a previous observation. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
polyvinyl chloride, case-control study, exposure matrix, testicular, cancer
in
International Journal of Cancer
volume
109
issue
3
pages
425 - 429
publisher
John Wiley & Sons
external identifiers
  • wos:000189245300016
  • pmid:14961582
  • scopus:1342288411
ISSN
0020-7136
DOI
10.1002/ijc.11709
language
English
LU publication?
yes
id
c60ff540-2fa7-46ff-953e-8286546aab78 (old id 286132)
date added to LUP
2007-10-22 14:52:26
date last changed
2017-01-22 03:33:33
@article{c60ff540-2fa7-46ff-953e-8286546aab78,
  abstract     = {Exposure to polyvinyl chloride. (PVC) plastics as a risk factor for testicular cancer was investigated. In total, 981 cases who were 20-75 years old and had reported to the Swedish Cancer Registry during 1993-1997 were included. One matched control from the population registry was used. Exposure was assessed by a questionnaire that was supplemented over the phone. Furthermore, an occupational hygienist qualified all exposures. In all, 791 matched pairs completed the questionnaire. Overall exposure to PVC plastics gave the odds ratio (OR)= 1.35, 95% confidence interval (Cl)= 1.06-1.71, increasing with > 10 year latency period to OR= 1.45, 95% Cl = 1.06-1.98. No dose-response relationships were found but rather an inverse relationship with the highest odds ratios in the lowest exposure category. In conclusion, no clear association with testicular cancer and exposure to PVC could be found in our study in contrast to a previous observation.},
  author       = {Hardell, L and Malmqvist, N and Ohlson, CG and Westberg, H and Eriksson, Mikael},
  issn         = {0020-7136},
  keyword      = {polyvinyl chloride,case-control study,exposure matrix,testicular,cancer},
  language     = {eng},
  number       = {3},
  pages        = {425--429},
  publisher    = {John Wiley & Sons},
  series       = {International Journal of Cancer},
  title        = {Testicular cancer and occupational exposure to polyvinyl chloride plastics: A case-control study},
  url          = {http://dx.doi.org/10.1002/ijc.11709},
  volume       = {109},
  year         = {2004},
}