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Novel method for the synthesis of molecularly imprinted polymer bead libraries

Kempe, Henrik LU and Kempe, Maria LU (2004) In Macromolecular Rapid Communications 25(1). p.315-320
Abstract
A novel method for the synthesis of spherical molecularly imprinted polymer (MIP) beads by suspension polymerization in mineral oil is described. The usefulness of the method was demonstrated by the synthesis of a propranolol imprinted MIP library. The composition of the library was generated by statistical experimental design. Multivariate data analysis correlated the screening data, obtained by a radioligand binding assay, to the composition of the MIPs.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
bead, spherical, molecular imprinting, chemometrics, combinatorial library, suspension polymerization
in
Macromolecular Rapid Communications
volume
25
issue
1
pages
315 - 320
publisher
John Wiley & Sons
external identifiers
  • wos:000188385300037
  • scopus:0442325291
ISSN
1022-1336
DOI
10.1002/marc.200300189
language
English
LU publication?
yes
id
9b969e2b-ae2f-47b2-96c6-1838da57adb0 (old id 288984)
date added to LUP
2007-10-23 18:16:47
date last changed
2017-10-22 03:49:42
@article{9b969e2b-ae2f-47b2-96c6-1838da57adb0,
  abstract     = {A novel method for the synthesis of spherical molecularly imprinted polymer (MIP) beads by suspension polymerization in mineral oil is described. The usefulness of the method was demonstrated by the synthesis of a propranolol imprinted MIP library. The composition of the library was generated by statistical experimental design. Multivariate data analysis correlated the screening data, obtained by a radioligand binding assay, to the composition of the MIPs.},
  author       = {Kempe, Henrik and Kempe, Maria},
  issn         = {1022-1336},
  keyword      = {bead,spherical,molecular imprinting,chemometrics,combinatorial library,suspension polymerization},
  language     = {eng},
  number       = {1},
  pages        = {315--320},
  publisher    = {John Wiley & Sons},
  series       = {Macromolecular Rapid Communications},
  title        = {Novel method for the synthesis of molecularly imprinted polymer bead libraries},
  url          = {http://dx.doi.org/10.1002/marc.200300189},
  volume       = {25},
  year         = {2004},
}