Advanced

Non-invasive diagnostics of the maxillary and frontal sinuses based on diode laser gas spectroscopy

Lewander, Märta LU ; Lindberg, Sven LU ; Svensson, Tomas LU ; Siemund, Roger LU ; Svanberg, Katarina LU and Svanberg, Sune LU (2012) In Rhinology 50(1). p.26-32
Abstract
Problem: Suspected, but objectively absent, rhinosinusitis constitutes a major cause of visits to the doctor, high health care costs, and the over-prescription of antibiotics, contributing to the serious problem of resistant bacteria. This situation is largely due to a lack of reliable and widely applicable diagnostic methods. Method: A novel method for the diagnosis of rhinosinusitis based on non-intrusive diode laser gas spectroscopy is presented. The technique is based on light absorption by free gas (oxygen and water vapour) inside the sinuses, and has the potential to be a complementary diagnostic tool in primary health care. The method was evaluated on 40 patients with suspected sinus problems, referred to the diagnostic radiology... (More)
Problem: Suspected, but objectively absent, rhinosinusitis constitutes a major cause of visits to the doctor, high health care costs, and the over-prescription of antibiotics, contributing to the serious problem of resistant bacteria. This situation is largely due to a lack of reliable and widely applicable diagnostic methods. Method: A novel method for the diagnosis of rhinosinusitis based on non-intrusive diode laser gas spectroscopy is presented. The technique is based on light absorption by free gas (oxygen and water vapour) inside the sinuses, and has the potential to be a complementary diagnostic tool in primary health care. The method was evaluated on 40 patients with suspected sinus problems, referred to the diagnostic radiology clinic for low-dose computed tomography (CT), which was used as the reference technique. Main results:The data obtained with the new laser-based method correlated well with the grading of opacification and ventilation using CT. The sensitivity and specificity were estimated to be 93% and 61%, respectively, for the maxillary sinuses, and 94% and 86%, respectively, for the frontal sinuses. Good reproducibility was shown. Principal conclusion: The laser-based technique presents real-time clinical data that correlate well to CT findings, while being non-intrusive and avoiding the use of ionizing radiation. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
paranasal sinus disease, diagnostic techniques and procedures, optical, device, laser, absorption
in
Rhinology
volume
50
issue
1
pages
26 - 32
publisher
International Rhinologic Society
external identifiers
  • wos:000304896000004
  • scopus:84862659369
ISSN
0300-0729
DOI
10.4193/Rhino10.231
language
English
LU publication?
yes
id
617ed79b-c808-4a05-8d82-7d8727b1e49e (old id 2906354)
date added to LUP
2012-08-01 09:45:53
date last changed
2017-09-10 04:22:42
@article{617ed79b-c808-4a05-8d82-7d8727b1e49e,
  abstract     = {Problem: Suspected, but objectively absent, rhinosinusitis constitutes a major cause of visits to the doctor, high health care costs, and the over-prescription of antibiotics, contributing to the serious problem of resistant bacteria. This situation is largely due to a lack of reliable and widely applicable diagnostic methods. Method: A novel method for the diagnosis of rhinosinusitis based on non-intrusive diode laser gas spectroscopy is presented. The technique is based on light absorption by free gas (oxygen and water vapour) inside the sinuses, and has the potential to be a complementary diagnostic tool in primary health care. The method was evaluated on 40 patients with suspected sinus problems, referred to the diagnostic radiology clinic for low-dose computed tomography (CT), which was used as the reference technique. Main results:The data obtained with the new laser-based method correlated well with the grading of opacification and ventilation using CT. The sensitivity and specificity were estimated to be 93% and 61%, respectively, for the maxillary sinuses, and 94% and 86%, respectively, for the frontal sinuses. Good reproducibility was shown. Principal conclusion: The laser-based technique presents real-time clinical data that correlate well to CT findings, while being non-intrusive and avoiding the use of ionizing radiation.},
  author       = {Lewander, Märta and Lindberg, Sven and Svensson, Tomas and Siemund, Roger and Svanberg, Katarina and Svanberg, Sune},
  issn         = {0300-0729},
  keyword      = {paranasal sinus disease,diagnostic techniques and procedures,optical,device,laser,absorption},
  language     = {eng},
  number       = {1},
  pages        = {26--32},
  publisher    = {International Rhinologic Society},
  series       = {Rhinology},
  title        = {Non-invasive diagnostics of the maxillary and frontal sinuses based on diode laser gas spectroscopy},
  url          = {http://dx.doi.org/10.4193/Rhino10.231},
  volume       = {50},
  year         = {2012},
}