Non-invasive diagnostics of the maxillary and frontal sinuses based on diode laser gas spectroscopy
(2012) In Rhinology 50(1). p.26-32- Abstract
- Problem: Suspected, but objectively absent, rhinosinusitis constitutes a major cause of visits to the doctor, high health care costs, and the over-prescription of antibiotics, contributing to the serious problem of resistant bacteria. This situation is largely due to a lack of reliable and widely applicable diagnostic methods. Method: A novel method for the diagnosis of rhinosinusitis based on non-intrusive diode laser gas spectroscopy is presented. The technique is based on light absorption by free gas (oxygen and water vapour) inside the sinuses, and has the potential to be a complementary diagnostic tool in primary health care. The method was evaluated on 40 patients with suspected sinus problems, referred to the diagnostic radiology... (More)
- Problem: Suspected, but objectively absent, rhinosinusitis constitutes a major cause of visits to the doctor, high health care costs, and the over-prescription of antibiotics, contributing to the serious problem of resistant bacteria. This situation is largely due to a lack of reliable and widely applicable diagnostic methods. Method: A novel method for the diagnosis of rhinosinusitis based on non-intrusive diode laser gas spectroscopy is presented. The technique is based on light absorption by free gas (oxygen and water vapour) inside the sinuses, and has the potential to be a complementary diagnostic tool in primary health care. The method was evaluated on 40 patients with suspected sinus problems, referred to the diagnostic radiology clinic for low-dose computed tomography (CT), which was used as the reference technique. Main results:The data obtained with the new laser-based method correlated well with the grading of opacification and ventilation using CT. The sensitivity and specificity were estimated to be 93% and 61%, respectively, for the maxillary sinuses, and 94% and 86%, respectively, for the frontal sinuses. Good reproducibility was shown. Principal conclusion: The laser-based technique presents real-time clinical data that correlate well to CT findings, while being non-intrusive and avoiding the use of ionizing radiation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2906354
- author
- Lewander, Märta LU ; Lindberg, Sven LU ; Svensson, Tomas LU ; Siemund, Roger LU ; Svanberg, Katarina LU and Svanberg, Sune LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- paranasal sinus disease, diagnostic techniques and procedures, optical, device, laser, absorption
- in
- Rhinology
- volume
- 50
- issue
- 1
- pages
- 26 - 32
- publisher
- University Hospital Utrecht
- external identifiers
-
- wos:000304896000004
- scopus:84862659369
- pmid:22469602
- ISSN
- 0300-0729
- DOI
- 10.4193/Rhino10.231
- language
- English
- LU publication?
- yes
- id
- 617ed79b-c808-4a05-8d82-7d8727b1e49e (old id 2906354)
- date added to LUP
- 2016-04-01 15:05:09
- date last changed
- 2025-10-14 11:53:27
@article{617ed79b-c808-4a05-8d82-7d8727b1e49e,
abstract = {{Problem: Suspected, but objectively absent, rhinosinusitis constitutes a major cause of visits to the doctor, high health care costs, and the over-prescription of antibiotics, contributing to the serious problem of resistant bacteria. This situation is largely due to a lack of reliable and widely applicable diagnostic methods. Method: A novel method for the diagnosis of rhinosinusitis based on non-intrusive diode laser gas spectroscopy is presented. The technique is based on light absorption by free gas (oxygen and water vapour) inside the sinuses, and has the potential to be a complementary diagnostic tool in primary health care. The method was evaluated on 40 patients with suspected sinus problems, referred to the diagnostic radiology clinic for low-dose computed tomography (CT), which was used as the reference technique. Main results:The data obtained with the new laser-based method correlated well with the grading of opacification and ventilation using CT. The sensitivity and specificity were estimated to be 93% and 61%, respectively, for the maxillary sinuses, and 94% and 86%, respectively, for the frontal sinuses. Good reproducibility was shown. Principal conclusion: The laser-based technique presents real-time clinical data that correlate well to CT findings, while being non-intrusive and avoiding the use of ionizing radiation.}},
author = {{Lewander, Märta and Lindberg, Sven and Svensson, Tomas and Siemund, Roger and Svanberg, Katarina and Svanberg, Sune}},
issn = {{0300-0729}},
keywords = {{paranasal sinus disease; diagnostic techniques and procedures; optical; device; laser; absorption}},
language = {{eng}},
number = {{1}},
pages = {{26--32}},
publisher = {{University Hospital Utrecht}},
series = {{Rhinology}},
title = {{Non-invasive diagnostics of the maxillary and frontal sinuses based on diode laser gas spectroscopy}},
url = {{http://dx.doi.org/10.4193/Rhino10.231}},
doi = {{10.4193/Rhino10.231}},
volume = {{50}},
year = {{2012}},
}