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Evaluation of screening procedures for congenital cataracts

Magnusson, G; Jakobsson, P; Kugelberg, U; Lundvall, A; Maly, E; Tornqvist, Kristina LU ; Abrahamsson, M; Andréasson, Bengt LU ; Borres, M and Broberger, U, et al. (2003) In Acta Pædiatrica 92(12). p.1468-1473
Abstract
Aim: To evaluate the efficacy of two different Swedish screening procedures for early detection of congenital cataracts in comparison with no screening. Methods: Children born between January 1992 and December 1998 in Swedish regions with an established eye-screening routine procedure, diagnosed with congenital cataract, and operated on before 1 y of age, were included in a retrospective study. Age at referral and age at time of the operation were compared between regions using different screening procedures: screening in the maternity wards (Region 1), at the well-baby clinics (Region 2) and one region without any screening (Region 3). Results: Seventy-two children were included in the study. Concerning early diagnosis and surgery, Region... (More)
Aim: To evaluate the efficacy of two different Swedish screening procedures for early detection of congenital cataracts in comparison with no screening. Methods: Children born between January 1992 and December 1998 in Swedish regions with an established eye-screening routine procedure, diagnosed with congenital cataract, and operated on before 1 y of age, were included in a retrospective study. Age at referral and age at time of the operation were compared between regions using different screening procedures: screening in the maternity wards (Region 1), at the well-baby clinics (Region 2) and one region without any screening (Region 3). Results: Seventy-two children were included in the study. Concerning early diagnosis and surgery, Region 1 differed significantly from Regions 2 and 3, which were more similar and were combined for further analysis. The difference in detected cases was greatest at 21 d of age (55% vs 18%; p < 0.001), but persisted even at 100 d of age (78% vs 64%; p < 0.02). Region 1 screening resulted in more and earlier cases detected than the other two regions (22 vs 15 per 100000 births). In 72% of all cases, surgery was performed in response to referrals from either the maternity wards (36%), or the well-baby clinics (36%). However, half of the cases from the well-baby clinics were detected too late, i.e. at >100 d. Conclusion: Eye screening in the maternity ward is preferable to well-baby clinic screening and to no screening at all, since it leads to early detection. Screening should also be performed routinely at well-baby clinics within the period when successful treatment is possible. (Less)
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publication status
published
subject
keywords
well-baby clinics, congenital cataract, blindness prevention, screening, newborn examination
in
Acta Pædiatrica
volume
92
issue
12
pages
1468 - 1473
publisher
Taylor & Francis
external identifiers
  • wos:000187845000021
  • pmid:14971800
  • scopus:9144247683
ISSN
1651-2227
DOI
10.1080/08035250310006476
language
English
LU publication?
yes
id
d8bd82f5-5f9d-441c-96ce-d69bd00424e7 (old id 291231)
date added to LUP
2007-09-18 07:02:38
date last changed
2017-01-01 06:37:59
@article{d8bd82f5-5f9d-441c-96ce-d69bd00424e7,
  abstract     = {Aim: To evaluate the efficacy of two different Swedish screening procedures for early detection of congenital cataracts in comparison with no screening. Methods: Children born between January 1992 and December 1998 in Swedish regions with an established eye-screening routine procedure, diagnosed with congenital cataract, and operated on before 1 y of age, were included in a retrospective study. Age at referral and age at time of the operation were compared between regions using different screening procedures: screening in the maternity wards (Region 1), at the well-baby clinics (Region 2) and one region without any screening (Region 3). Results: Seventy-two children were included in the study. Concerning early diagnosis and surgery, Region 1 differed significantly from Regions 2 and 3, which were more similar and were combined for further analysis. The difference in detected cases was greatest at 21 d of age (55% vs 18%; p &lt; 0.001), but persisted even at 100 d of age (78% vs 64%; p &lt; 0.02). Region 1 screening resulted in more and earlier cases detected than the other two regions (22 vs 15 per 100000 births). In 72% of all cases, surgery was performed in response to referrals from either the maternity wards (36%), or the well-baby clinics (36%). However, half of the cases from the well-baby clinics were detected too late, i.e. at &gt;100 d. Conclusion: Eye screening in the maternity ward is preferable to well-baby clinic screening and to no screening at all, since it leads to early detection. Screening should also be performed routinely at well-baby clinics within the period when successful treatment is possible.},
  author       = {Magnusson, G and Jakobsson, P and Kugelberg, U and Lundvall, A and Maly, E and Tornqvist, Kristina and Abrahamsson, M and Andréasson, Bengt and Borres, M and Broberger, U and Hellstrom-Westas, L and Kornfält, Ragnhild and Nelson, N and Sjostrand, J and Thiringer, K},
  issn         = {1651-2227},
  keyword      = {well-baby clinics,congenital cataract,blindness prevention,screening,newborn examination},
  language     = {eng},
  number       = {12},
  pages        = {1468--1473},
  publisher    = {Taylor & Francis},
  series       = {Acta Pædiatrica},
  title        = {Evaluation of screening procedures for congenital cataracts},
  url          = {http://dx.doi.org/10.1080/08035250310006476},
  volume       = {92},
  year         = {2003},
}