Discordant HER2 overexpression in primary and metastatic upper gastrointestinal adenocarcinoma signifies poor prognosis.
Hedner, Charlotta LU ; Tran, Lena ; Borg, David LU ; Nodin, Björn LU ; Jirström, Karin LU
and Eberhard, Jakob
LU
(2015)
In Histopathology
- Abstract
- Targeted therapy with trastuzumab has proven to be effective for patients with gastric cancer overexpressing the human epidermal growth factor receptor 2 (HER2). Further studies are needed to determine the best method for assessment of HER2 overexpression. Moreover, the prognostic value of HER2 overexpression, including the significance of tumour heterogeneity, remains unclear.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/5442112
- author
- Hedner, Charlotta
LU
; Tran, Lena
; Borg, David
LU
; Nodin, Björn
LU
; Jirström, Karin
LU
and Eberhard, Jakob
LU
- organization
- publishing date
- 2015-05-27
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Histopathology
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:26016514
- scopus:84955203043
- pmid:26016514
- ISSN
- 0309-0167
- DOI
- 10.1111/his.12744
- language
- English
- LU publication?
- yes
- id
- 2925b5f3-6080-4594-a782-ed02f25df724 (old id 5442112)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26016514?dopt=Abstract
- date added to LUP
- 2016-04-04 07:31:30
- date last changed
- 2024-01-29 02:52:54
@article{2925b5f3-6080-4594-a782-ed02f25df724,
abstract = {{Targeted therapy with trastuzumab has proven to be effective for patients with gastric cancer overexpressing the human epidermal growth factor receptor 2 (HER2). Further studies are needed to determine the best method for assessment of HER2 overexpression. Moreover, the prognostic value of HER2 overexpression, including the significance of tumour heterogeneity, remains unclear.}},
author = {{Hedner, Charlotta and Tran, Lena and Borg, David and Nodin, Björn and Jirström, Karin and Eberhard, Jakob}},
issn = {{0309-0167}},
language = {{eng}},
month = {{05}},
publisher = {{Wiley-Blackwell}},
series = {{Histopathology}},
title = {{Discordant HER2 overexpression in primary and metastatic upper gastrointestinal adenocarcinoma signifies poor prognosis.}},
url = {{http://dx.doi.org/10.1111/his.12744}},
doi = {{10.1111/his.12744}},
year = {{2015}},
}