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S100B and cardiac surgery: Possibilities and limitations

Bjursten, Henrik LU (2003) In Restorative Neurology and Neuroscience 21(3-4). p.151-157
Abstract
Serum determinations of the glial protein S100B has been found to correlate with brain damage after cardiac surgery. Forty-eight hours and later after surgery, increased S100B levels correlates with the presence of brain infarction, and the extent of infracted brain tissue. S100B at this time-point has been shown to predict long-term outcome, higher S100B levels correlated with decreased survival. Early levels (2-8 hours after surgery) of S100B have shown disparate results when trying to correlate it with postoperative cognitive decline. One reason for the lack of strong correlation could be the contamination of S100B from shed blood the first hours after surgery.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Restorative Neurology and Neuroscience
volume
21
issue
3-4
pages
151 - 157
publisher
IOS Press
external identifiers
  • wos:000186690900007
  • scopus:0142226853
ISSN
1878-3627
language
English
LU publication?
yes
id
920557a0-c3e0-4240-87b6-968235120bfa (old id 294781)
alternative location
http://iospress.metapress.com/link.asp?id=enjkr7719v6pwf9j
date added to LUP
2007-09-13 14:33:36
date last changed
2017-01-01 07:26:33
@article{920557a0-c3e0-4240-87b6-968235120bfa,
  abstract     = {Serum determinations of the glial protein S100B has been found to correlate with brain damage after cardiac surgery. Forty-eight hours and later after surgery, increased S100B levels correlates with the presence of brain infarction, and the extent of infracted brain tissue. S100B at this time-point has been shown to predict long-term outcome, higher S100B levels correlated with decreased survival. Early levels (2-8 hours after surgery) of S100B have shown disparate results when trying to correlate it with postoperative cognitive decline. One reason for the lack of strong correlation could be the contamination of S100B from shed blood the first hours after surgery.},
  author       = {Bjursten, Henrik},
  issn         = {1878-3627},
  language     = {eng},
  number       = {3-4},
  pages        = {151--157},
  publisher    = {IOS Press},
  series       = {Restorative Neurology and Neuroscience},
  title        = {S100B and cardiac surgery: Possibilities and limitations},
  volume       = {21},
  year         = {2003},
}