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Normal intersubject threshold variability and normal limits of the SITA SWAP and full threshold SWAP perimetric programs

Bengtsson, Boel LU and Heijl, Anders LU (2003) In Investigative Ophthalmology & Visual Science 44(11). p.5029-5034
Abstract
PURPOSE. To compare intersubject variability and normal limits of threshold values between the new Swedish interactive test algorithm short wavelength automated perimetry (SITA SWAP) and the older Full Threshold SWAP programs (Carl Zeiss Meditec, Dublin, CA). METHODS. Normal reduction of differential tight sensitivity with age, age-corrected thresholds, intersubject variability, and normal limits of sensitivity were calculated from SITA SWAP and Full Threshold SWAP fields obtained in 53 normal subjects between 20 and 72 years of age. RESULTS. Age influence on threshold sensitivity was the same with the two SWAP programs. On average, sensitivity decreased by 0.13 dB per year of age. Age-corrected normal threshold sensitivity was... (More)
PURPOSE. To compare intersubject variability and normal limits of threshold values between the new Swedish interactive test algorithm short wavelength automated perimetry (SITA SWAP) and the older Full Threshold SWAP programs (Carl Zeiss Meditec, Dublin, CA). METHODS. Normal reduction of differential tight sensitivity with age, age-corrected thresholds, intersubject variability, and normal limits of sensitivity were calculated from SITA SWAP and Full Threshold SWAP fields obtained in 53 normal subjects between 20 and 72 years of age. RESULTS. Age influence on threshold sensitivity was the same with the two SWAP programs. On average, sensitivity decreased by 0.13 dB per year of age. Age-corrected normal threshold sensitivity was significantly higher (P < 0.0001) for SITA SWAP than for Full Threshold SWAP. The means for a subject 45.4 years of age were 28.8 dB with SITA SWAP and 24.4 dB with Full Threshold SWAP. Intersubject variance was 22% smaller with SITA SWAP than with Full Threshold SWAP. Normal limits at the P < 5% significance level were, on average, 14% narrower with SITA SWAP than with Full Threshold SWAP using Total Deviations from age-corrected normal thresholds and 11% narrower when applying Pattern Deviation, which is intended to adjust for general depression or elevation of the field. CONCLUSIONS. SITA SWAP test results from normal eyes showed higher sensitivities than results from the older Full Threshold SWAP. This represents an increase of the dynamic range, which implies that more patients can be tested with SWAP. The smaller intersubject variability with SITA SWAP means narrower normal limits and may be associated with more sensitive probability maps. (Less)
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author
organization
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type
Contribution to journal
publication status
published
subject
in
Investigative Ophthalmology & Visual Science
volume
44
issue
11
pages
5029 - 5034
publisher
ASSOC RESEARCH VISION OPHTHALMOLOGY INC
external identifiers
  • wos:000186231800058
  • pmid:14578431
  • scopus:0142200815
ISSN
1552-5783
DOI
10.1167/iovs.02-1220
language
English
LU publication?
yes
id
54897448-ac91-49b7-8459-a7ec709ddc12 (old id 296474)
date added to LUP
2007-08-23 07:46:01
date last changed
2018-05-29 11:32:02
@article{54897448-ac91-49b7-8459-a7ec709ddc12,
  abstract     = {PURPOSE. To compare intersubject variability and normal limits of threshold values between the new Swedish interactive test algorithm short wavelength automated perimetry (SITA SWAP) and the older Full Threshold SWAP programs (Carl Zeiss Meditec, Dublin, CA). METHODS. Normal reduction of differential tight sensitivity with age, age-corrected thresholds, intersubject variability, and normal limits of sensitivity were calculated from SITA SWAP and Full Threshold SWAP fields obtained in 53 normal subjects between 20 and 72 years of age. RESULTS. Age influence on threshold sensitivity was the same with the two SWAP programs. On average, sensitivity decreased by 0.13 dB per year of age. Age-corrected normal threshold sensitivity was significantly higher (P &lt; 0.0001) for SITA SWAP than for Full Threshold SWAP. The means for a subject 45.4 years of age were 28.8 dB with SITA SWAP and 24.4 dB with Full Threshold SWAP. Intersubject variance was 22% smaller with SITA SWAP than with Full Threshold SWAP. Normal limits at the P &lt; 5% significance level were, on average, 14% narrower with SITA SWAP than with Full Threshold SWAP using Total Deviations from age-corrected normal thresholds and 11% narrower when applying Pattern Deviation, which is intended to adjust for general depression or elevation of the field. CONCLUSIONS. SITA SWAP test results from normal eyes showed higher sensitivities than results from the older Full Threshold SWAP. This represents an increase of the dynamic range, which implies that more patients can be tested with SWAP. The smaller intersubject variability with SITA SWAP means narrower normal limits and may be associated with more sensitive probability maps.},
  author       = {Bengtsson, Boel and Heijl, Anders},
  issn         = {1552-5783},
  language     = {eng},
  number       = {11},
  pages        = {5029--5034},
  publisher    = {ASSOC RESEARCH VISION OPHTHALMOLOGY INC},
  series       = {Investigative Ophthalmology & Visual Science},
  title        = {Normal intersubject threshold variability and normal limits of the SITA SWAP and full threshold SWAP perimetric programs},
  url          = {http://dx.doi.org/10.1167/iovs.02-1220},
  volume       = {44},
  year         = {2003},
}