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Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis.

Vult von Steyern, Kristina LU ; Björkman-Burtscher, Isabella LU ; Höglund, Peter; Bozovic, Gracijela LU ; Wiklund, Marie and Geijer, Mats LU (2012) In European Radiology 22(12). p.2718-2728
Abstract
OBJECTIVES:

To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis.



METHODS:

A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system.



RESULTS:

Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally... (More)
OBJECTIVES:

To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis.



METHODS:

A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system.



RESULTS:

Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa >0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85).



CONCLUSIONS:

The tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity.



KEY POINTS :

• Tomosynthesis is more sensitive than conventional radiography for pulmonary cystic fibrosis changes. • The radiation dose from chest tomosynthesis is low compared with computed tomography. • Tomosynthesis may become useful in the regular follow-up of patients with cystic fibrosis. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Radiology
volume
22
issue
12
pages
2718 - 2728
publisher
Springer
external identifiers
  • wos:000310590400019
  • pmid:22752406
  • scopus:84870353191
ISSN
0938-7994
DOI
10.1007/s00330-012-2534-y
language
English
LU publication?
yes
id
f51fbd4d-4660-4493-adb4-a227e0ad779a (old id 2967592)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22752406?dopt=Abstract
date added to LUP
2012-08-09 14:03:53
date last changed
2017-04-09 03:09:15
@article{f51fbd4d-4660-4493-adb4-a227e0ad779a,
  abstract     = {OBJECTIVES: <br/><br>
To design and validate a scoring system for tomosynthesis (digital tomography) in pulmonary cystic fibrosis. <br/><br>
<br/><br>
METHODS: <br/><br>
A scoring system dedicated to tomosynthesis in pulmonary cystic fibrosis was designed. Three radiologists independently scored 88 pairs of radiographs and tomosynthesis examinations of the chest in 60 patients with cystic fibrosis and 7 oncology patients. Radiographs were scored according to the Brasfield scoring system and tomosynthesis examinations were scored using the new scoring system. <br/><br>
<br/><br>
RESULTS: <br/><br>
Observer agreements for the tomosynthesis score were almost perfect for the total score with square-weighted kappa &gt;0.90, and generally substantial to almost perfect for subscores. Correlation between the tomosynthesis score and the Brasfield score was good for the three observers (Kendall's rank correlation tau 0.68, 0.77 and 0.78). Tomosynthesis was generally scored higher as a percentage of the maximum score. Observer agreements for the total score for Brasfield score were almost perfect (square-weighted kappa 0.80, 0.81 and 0.85). <br/><br>
<br/><br>
CONCLUSIONS: <br/><br>
The tomosynthesis scoring system seems robust and correlates well with the Brasfield score. Compared with radiography, tomosynthesis is more sensitive to cystic fibrosis changes, especially bronchiectasis and mucus plugging, and the new tomosynthesis scoring system offers the possibility of more detailed and accurate scoring of disease severity. <br/><br>
<br/><br>
KEY POINTS : <br/><br>
• Tomosynthesis is more sensitive than conventional radiography for pulmonary cystic fibrosis changes. • The radiation dose from chest tomosynthesis is low compared with computed tomography. • Tomosynthesis may become useful in the regular follow-up of patients with cystic fibrosis.},
  author       = {Vult von Steyern, Kristina and Björkman-Burtscher, Isabella and Höglund, Peter and Bozovic, Gracijela and Wiklund, Marie and Geijer, Mats},
  issn         = {0938-7994},
  language     = {eng},
  number       = {12},
  pages        = {2718--2728},
  publisher    = {Springer},
  series       = {European Radiology},
  title        = {Description and validation of a scoring system for tomosynthesis in pulmonary cystic fibrosis.},
  url          = {http://dx.doi.org/10.1007/s00330-012-2534-y},
  volume       = {22},
  year         = {2012},
}