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Thermodynamics of binding of alpha-cyclodextrin to straight-chain alkyl derivatives in aqueous solution

Stödeman, Magnus LU ; Gomez-Orellana, I and Hallen, D (2003) In Journal of Inclusion Phenomena and Molecular Recognition in Chemistry 46(3-4). p.125-132
Abstract
Apparent standard Gibbs energy, enthalpy, entropy, and heat capacity data of the interactions of alpha-cyclodextrin (alphaCD) to some n-carboxylates H(CH2)(n)COO- (n = 4 - 6), are determined by isothermal titration microcalorimetry at different temperatures in phosphate buffer, pH 9.0, assuming a 1 : 1 model in dilute solution. Modelling of contributions of the thermodynamic properties of the solution indicates that aCD undergoes conformational change upon binding to homologous series of n-carboxylates, n-alcohols, alpha,omega-alkane dicarboxylates and alpha,omega-alkane diols.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
complex formation, alpha-cyclodextrin, alkyl derivatives, microcalorimetry
in
Journal of Inclusion Phenomena and Molecular Recognition in Chemistry
volume
46
issue
3-4
pages
125 - 132
publisher
Springer
external identifiers
  • wos:000186271000002
  • scopus:3543015016
ISSN
0923-0750
DOI
10.1023/A:1026380832331
language
English
LU publication?
yes
id
c44a1eae-4ace-4bef-a5a9-d665c9cb5704 (old id 297153)
date added to LUP
2007-09-22 12:53:06
date last changed
2018-01-07 08:34:46
@article{c44a1eae-4ace-4bef-a5a9-d665c9cb5704,
  abstract     = {Apparent standard Gibbs energy, enthalpy, entropy, and heat capacity data of the interactions of alpha-cyclodextrin (alphaCD) to some n-carboxylates H(CH2)(n)COO- (n = 4 - 6), are determined by isothermal titration microcalorimetry at different temperatures in phosphate buffer, pH 9.0, assuming a 1 : 1 model in dilute solution. Modelling of contributions of the thermodynamic properties of the solution indicates that aCD undergoes conformational change upon binding to homologous series of n-carboxylates, n-alcohols, alpha,omega-alkane dicarboxylates and alpha,omega-alkane diols.},
  author       = {Stödeman, Magnus and Gomez-Orellana, I and Hallen, D},
  issn         = {0923-0750},
  keyword      = {complex formation,alpha-cyclodextrin,alkyl derivatives,microcalorimetry},
  language     = {eng},
  number       = {3-4},
  pages        = {125--132},
  publisher    = {Springer},
  series       = {Journal of Inclusion Phenomena and Molecular Recognition in Chemistry},
  title        = {Thermodynamics of binding of alpha-cyclodextrin to straight-chain alkyl derivatives in aqueous solution},
  url          = {http://dx.doi.org/10.1023/A:1026380832331},
  volume       = {46},
  year         = {2003},
}