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Antimicrobial Peptides in Cutaneous Wound Healing

Sørensen, Ole E LU (2016) In Birkhäuser Advances in Infectious Diseases p.1-15
Abstract
Injury that breached the physical skin barrier increases the likelihood of infection. The wound healing process is divided into hemostasis, inflammation, proliferation, and tissue remodeling. Antimicrobial peptides play a major role for the antimicrobial defense at all these stages in wound healing, but the main sources of antimicrobial peptides vary with the different stages of wound healing coming from plasma proteins, neutrophils, and keratinocytes. Apart from being part of the antimicrobial defense, antimicrobial peptides play other important roles in wound healing as in angiogenesis, attraction of leukocytes, resolution of inflammation, and proliferation. Future studies will demonstrate whether antimicrobial peptides can be used... (More)
Injury that breached the physical skin barrier increases the likelihood of infection. The wound healing process is divided into hemostasis, inflammation, proliferation, and tissue remodeling. Antimicrobial peptides play a major role for the antimicrobial defense at all these stages in wound healing, but the main sources of antimicrobial peptides vary with the different stages of wound healing coming from plasma proteins, neutrophils, and keratinocytes. Apart from being part of the antimicrobial defense, antimicrobial peptides play other important roles in wound healing as in angiogenesis, attraction of leukocytes, resolution of inflammation, and proliferation. Future studies will demonstrate whether antimicrobial peptides can be used therapeutically to improve the wound healing processes and reduce scar formation in chronic wounds. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Antimicrobial peptides : Role in Human Health and Disease - Role in Human Health and Disease
series title
Birkhäuser Advances in Infectious Diseases
editor
Harder, J. and Schröder, J-M.
pages
1 - 15
publisher
Springer
external identifiers
  • scopus:85045418454
ISSN
2504-3811
ISBN
978-3-319-24197-5
978-3-319-24199-9
DOI
10.1007/978-3-319-24199-9_1
language
English
LU publication?
yes
id
2a13f72a-ae47-469f-a899-dc49f4a665b0
date added to LUP
2018-03-21 11:59:43
date last changed
2024-06-24 11:44:55
@inbook{2a13f72a-ae47-469f-a899-dc49f4a665b0,
  abstract     = {{Injury that breached the physical skin barrier increases the likelihood of infection. The wound healing process is divided into hemostasis, inflammation, proliferation, and tissue remodeling. Antimicrobial peptides play a major role for the antimicrobial defense at all these stages in wound healing, but the main sources of antimicrobial peptides vary with the different stages of wound healing coming from plasma proteins, neutrophils, and keratinocytes. Apart from being part of the antimicrobial defense, antimicrobial peptides play other important roles in wound healing as in angiogenesis, attraction of leukocytes, resolution of inflammation, and proliferation. Future studies will demonstrate whether antimicrobial peptides can be used therapeutically to improve the wound healing processes and reduce scar formation in chronic wounds.}},
  author       = {{Sørensen, Ole E}},
  booktitle    = {{Antimicrobial peptides : Role in Human Health and Disease}},
  editor       = {{Harder, J. and Schröder, J-M.}},
  isbn         = {{978-3-319-24197-5}},
  issn         = {{2504-3811}},
  language     = {{eng}},
  pages        = {{1--15}},
  publisher    = {{Springer}},
  series       = {{Birkhäuser Advances in Infectious Diseases}},
  title        = {{Antimicrobial Peptides in Cutaneous Wound Healing}},
  url          = {{http://dx.doi.org/10.1007/978-3-319-24199-9_1}},
  doi          = {{10.1007/978-3-319-24199-9_1}},
  year         = {{2016}},
}