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Low Free Testosterone is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.

Antonio, Leen ; Wu, Frederick C W ; O'Neill, Terence W ; Pye, Stephen R ; Ahern, Tomas B ; Laurent, Michaël R ; Huhtaniemi, Ilpo T ; Lean, Michael E J ; Keevil, Brian G and Rastrelli, Giulia , et al. (2016) In The Journal of clinical endocrinology and metabolism 101(7). p.2647-2657
Abstract
During ageing, total testosterone (TT) declines and SHBG increases, resulting in a greater decrease in calculated free testosterone (cFT). Currently, guidelines suggest using TT to diagnose androgen deficiency and to reserve cFT only for men with borderline TT.
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
The Journal of clinical endocrinology and metabolism
volume
101
issue
7
pages
2647 - 2657
publisher
Oxford University Press
external identifiers
  • pmid:26909800
  • scopus:84978079951
  • wos:000380224800006
  • pmid:26909800
ISSN
1945-7197
DOI
10.1210/jc.2015-4106
language
English
LU publication?
yes
id
2a22ff4e-3b72-4c2d-9e97-8cb33efa637d (old id 8821806)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26909800?dopt=Abstract
date added to LUP
2016-04-04 09:14:51
date last changed
2022-05-09 04:04:05
@article{2a22ff4e-3b72-4c2d-9e97-8cb33efa637d,
  abstract     = {{During ageing, total testosterone (TT) declines and SHBG increases, resulting in a greater decrease in calculated free testosterone (cFT). Currently, guidelines suggest using TT to diagnose androgen deficiency and to reserve cFT only for men with borderline TT.}},
  author       = {{Antonio, Leen and Wu, Frederick C W and O'Neill, Terence W and Pye, Stephen R and Ahern, Tomas B and Laurent, Michaël R and Huhtaniemi, Ilpo T and Lean, Michael E J and Keevil, Brian G and Rastrelli, Giulia and Forti, Gianni and Bartfai, György and Casanueva, Felipe F and Kula, Krzysztof and Punab, Margus and Giwercman, Aleksander and Claessens, Frank and Decallonne, Brigitte and Vanderschueren, Dirk}},
  issn         = {{1945-7197}},
  language     = {{eng}},
  number       = {{7}},
  pages        = {{2647--2657}},
  publisher    = {{Oxford University Press}},
  series       = {{The Journal of clinical endocrinology and metabolism}},
  title        = {{Low Free Testosterone is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone.}},
  url          = {{http://dx.doi.org/10.1210/jc.2015-4106}},
  doi          = {{10.1210/jc.2015-4106}},
  volume       = {{101}},
  year         = {{2016}},
}