Proteomic analysis of cell fate decision
(2013) In Current Opinion in Genetics & Development 23(5). p.7-540- Abstract
The field of proteomics is progressing at a rapid pace, developing from primarily a specialist technology to a valuable tool in biological research. Importantly, the establishment of mass spectrometry as a quantitative method, miniaturisation of liquid chromatography techniques, and improved sensitivity of mass-spectrometric instrumentation now enable near-complete monitoring of cellular proteome dynamics. An increasing number of studies are therefore now applying quantitative proteomics to study proteins and posttranslational modifications in stem cells, to reveal molecular mechanisms and pathways underlying pluripotency, differentiation and reprogramming.
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https://lup.lub.lu.se/record/2a3af651-0961-475c-b0a0-30be595762df
- author
- Hansson, Jenny LU and Krijgsveld, Jeroen
- organization
- publishing date
- 2013-10
- type
- Contribution to journal
- publication status
- published
- keywords
- Cell Differentiation, Cell Lineage, Cellular Reprogramming, Chromatography, Liquid, Humans, Induced Pluripotent Stem Cells, Mass Spectrometry, Protein Processing, Post-Translational, Proteome, Proteomics, Signal Transduction
- in
- Current Opinion in Genetics & Development
- volume
- 23
- issue
- 5
- pages
- 8 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:23942315
- scopus:84883826084
- ISSN
- 1879-0380
- DOI
- 10.1016/j.gde.2013.06.004
- language
- English
- LU publication?
- no
- id
- 2a3af651-0961-475c-b0a0-30be595762df
- date added to LUP
- 2016-04-19 10:19:35
- date last changed
- 2024-09-06 09:39:13
@article{2a3af651-0961-475c-b0a0-30be595762df, abstract = {{<p>The field of proteomics is progressing at a rapid pace, developing from primarily a specialist technology to a valuable tool in biological research. Importantly, the establishment of mass spectrometry as a quantitative method, miniaturisation of liquid chromatography techniques, and improved sensitivity of mass-spectrometric instrumentation now enable near-complete monitoring of cellular proteome dynamics. An increasing number of studies are therefore now applying quantitative proteomics to study proteins and posttranslational modifications in stem cells, to reveal molecular mechanisms and pathways underlying pluripotency, differentiation and reprogramming.</p>}}, author = {{Hansson, Jenny and Krijgsveld, Jeroen}}, issn = {{1879-0380}}, keywords = {{Cell Differentiation; Cell Lineage; Cellular Reprogramming; Chromatography, Liquid; Humans; Induced Pluripotent Stem Cells; Mass Spectrometry; Protein Processing, Post-Translational; Proteome; Proteomics; Signal Transduction}}, language = {{eng}}, number = {{5}}, pages = {{7--540}}, publisher = {{Elsevier}}, series = {{Current Opinion in Genetics & Development}}, title = {{Proteomic analysis of cell fate decision}}, url = {{http://dx.doi.org/10.1016/j.gde.2013.06.004}}, doi = {{10.1016/j.gde.2013.06.004}}, volume = {{23}}, year = {{2013}}, }