Transient increase in glucose variability during Ramadan fasting in patients with insulin-treated type 2 diabetes : A preliminary study
(2023) In Diabetes & metabolic syndrome 17(4).- Abstract
AIM: We aimed to examine the effect of Ramadan fasting on interstitial glucose control and variability before, during, and after Ramadan in type 2 diabetes patients receiving insulin therapy.
METHODS: Participants received a flash glucose monitoring (FGM) system one week before Ramadan that was removed on the sixth or seventh day (pre- and early Ramadan periods) of Ramadan and a second FGM system one week before the end of Ramadan that was removed one week after the end of Ramadan (late and post-Ramadan periods). Fasting blood samples were collected during the pre-, early, and late Ramadan study visits and tested for HbA1c, serum creatinine, and plasma glucose levels.
RESULTS: Thirty-four patients were prospectively... (More)
AIM: We aimed to examine the effect of Ramadan fasting on interstitial glucose control and variability before, during, and after Ramadan in type 2 diabetes patients receiving insulin therapy.
METHODS: Participants received a flash glucose monitoring (FGM) system one week before Ramadan that was removed on the sixth or seventh day (pre- and early Ramadan periods) of Ramadan and a second FGM system one week before the end of Ramadan that was removed one week after the end of Ramadan (late and post-Ramadan periods). Fasting blood samples were collected during the pre-, early, and late Ramadan study visits and tested for HbA1c, serum creatinine, and plasma glucose levels.
RESULTS: Thirty-four patients were prospectively included. The standard deviation and coefficient of variation of glucose concentrations were higher in the early Ramadan period than in the pre-Ramadan period, but did not differ in the late or post-Ramadan periods. Changes in the early Ramadan period were restricted to males and patients aged <55 years. No significant changes were observed in the average glucose level, glucose management indicator, time in range, time in hyperglycemia, or time in hypoglycemia at any time point.
CONCLUSIONS: Ramadan fasting in patients with insulin-treated type 2 diabetes is associated with an initial increase in glucose variability that quickly returned to pre-Ramadan levels. Ramadan fasting was not associated with any significant changes in glycemic control measures.
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- author
- Elmalti, Akrem ; Mukhtar, Mamoun ; Kenz, Sami ; Skaria, Sijomol and Elgzyri, Targ LU
- organization
- publishing date
- 2023-04
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Ramadan, Glucose variability, Diabetes, Insulin
- in
- Diabetes & metabolic syndrome
- volume
- 17
- issue
- 4
- article number
- 102745
- pages
- 5 pages
- publisher
- Elsevier
- external identifiers
-
- scopus:85151076361
- pmid:37001416
- ISSN
- 1871-4021
- DOI
- 10.1016/j.dsx.2023.102745
- language
- English
- LU publication?
- yes
- additional info
- Copyright © 2023 Research Trust of DiabetesIndia (DiabetesIndia) and National Diabetes Obesity and Cholesterol Foundation (N-DOC). Published by Elsevier Ltd. All rights reserved.
- id
- 2a3b2b47-13c0-4d43-a0cc-2162b24e1192
- date added to LUP
- 2023-05-08 11:36:19
- date last changed
- 2024-06-15 02:46:25
@article{2a3b2b47-13c0-4d43-a0cc-2162b24e1192,
abstract = {{<p>AIM: We aimed to examine the effect of Ramadan fasting on interstitial glucose control and variability before, during, and after Ramadan in type 2 diabetes patients receiving insulin therapy.</p><p>METHODS: Participants received a flash glucose monitoring (FGM) system one week before Ramadan that was removed on the sixth or seventh day (pre- and early Ramadan periods) of Ramadan and a second FGM system one week before the end of Ramadan that was removed one week after the end of Ramadan (late and post-Ramadan periods). Fasting blood samples were collected during the pre-, early, and late Ramadan study visits and tested for HbA1c, serum creatinine, and plasma glucose levels.</p><p>RESULTS: Thirty-four patients were prospectively included. The standard deviation and coefficient of variation of glucose concentrations were higher in the early Ramadan period than in the pre-Ramadan period, but did not differ in the late or post-Ramadan periods. Changes in the early Ramadan period were restricted to males and patients aged <55 years. No significant changes were observed in the average glucose level, glucose management indicator, time in range, time in hyperglycemia, or time in hypoglycemia at any time point.</p><p>CONCLUSIONS: Ramadan fasting in patients with insulin-treated type 2 diabetes is associated with an initial increase in glucose variability that quickly returned to pre-Ramadan levels. Ramadan fasting was not associated with any significant changes in glycemic control measures.</p>}},
author = {{Elmalti, Akrem and Mukhtar, Mamoun and Kenz, Sami and Skaria, Sijomol and Elgzyri, Targ}},
issn = {{1871-4021}},
keywords = {{Ramadan; Glucose variability; Diabetes; Insulin}},
language = {{eng}},
number = {{4}},
publisher = {{Elsevier}},
series = {{Diabetes & metabolic syndrome}},
title = {{Transient increase in glucose variability during Ramadan fasting in patients with insulin-treated type 2 diabetes : A preliminary study}},
url = {{http://dx.doi.org/10.1016/j.dsx.2023.102745}},
doi = {{10.1016/j.dsx.2023.102745}},
volume = {{17}},
year = {{2023}},
}