Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)
(2018) In British Journal of Dermatology 178(5). p.332-341- Abstract
This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12–14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus over the definition of the core domain of long-term control and how to measure it and (ii) to prioritize future areas of research for the measurement of the core domain of quality of life (QoL) in children. Moderated whole-group and small-group consensus discussions were informed by presentations of qualitative studies, systematic reviews and validation studies. Small-group allocations were performed a priori to ensure that each group included different stakeholders from a variety of... (More)
This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12–14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus over the definition of the core domain of long-term control and how to measure it and (ii) to prioritize future areas of research for the measurement of the core domain of quality of life (QoL) in children. Moderated whole-group and small-group consensus discussions were informed by presentations of qualitative studies, systematic reviews and validation studies. Small-group allocations were performed a priori to ensure that each group included different stakeholders from a variety of geographical regions. Anonymous whole-group voting was carried out using handheld electronic voting pads according to predefined consensus rules. It was agreed by consensus that the long-term control domain should include signs, symptoms, quality of life and a patient global instrument. The group agreed that itch intensity should be measured when assessing long-term control of eczema in addition to the frequency of itch captured by the symptoms domain. There was no recommendation of an instrument for the core outcome domain of quality of life in children, but existing instruments were assessed for face validity and feasibility, and future work that will facilitate the recommendation of an instrument was agreed upon.
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- author
- author collaboration
- organization
- publishing date
- 2018-05-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Dermatology
- volume
- 178
- issue
- 5
- pages
- 332 - 341
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85047548967
- pmid:29672835
- ISSN
- 0007-0963
- DOI
- 10.1111/bjd.16543
- language
- English
- LU publication?
- yes
- id
- 2b6c6afb-1f55-4cc4-adac-12a030444b84
- date added to LUP
- 2020-06-08 16:59:49
- date last changed
- 2024-04-17 10:23:13
@article{2b6c6afb-1f55-4cc4-adac-12a030444b84,
abstract = {{<p>This is the report from the fifth meeting of the Harmonising Outcome Measures for Eczema initiative (HOME V). The meeting was held on 12–14 June 2017 in Nantes, France, with 81 participants. The main aims of the meeting were (i) to achieve consensus over the definition of the core domain of long-term control and how to measure it and (ii) to prioritize future areas of research for the measurement of the core domain of quality of life (QoL) in children. Moderated whole-group and small-group consensus discussions were informed by presentations of qualitative studies, systematic reviews and validation studies. Small-group allocations were performed a priori to ensure that each group included different stakeholders from a variety of geographical regions. Anonymous whole-group voting was carried out using handheld electronic voting pads according to predefined consensus rules. It was agreed by consensus that the long-term control domain should include signs, symptoms, quality of life and a patient global instrument. The group agreed that itch intensity should be measured when assessing long-term control of eczema in addition to the frequency of itch captured by the symptoms domain. There was no recommendation of an instrument for the core outcome domain of quality of life in children, but existing instruments were assessed for face validity and feasibility, and future work that will facilitate the recommendation of an instrument was agreed upon.</p>}},
author = {{Chalmers, J. R. and Apfelbacher, C. and Williams, H. C. and Prinsen, C. A. and Spuls, P. I. and Simpson, E. and Gerbens, L. A.A. and Boers, M. and Barbarot, S. and Stalder, J. F. and Abuabara, K. and Aoki, V. and Ardeleanu, M. and Armstrong, J. and Bang, B. and Berents, T. L. and Burton, T. and Butler, L. and Chubachi, T. and Cresswell-Melville, A. and DeLozier, A. and Eckert, L. and Eichenfield, L. and Flohr, C. and Futamura, M. and Gadkari, A. and Gjerde, E. S. and van Halewijn, K. F. and Hawkes, C. and Howells, L. and Howie, L. and Humphreys, R. and Ishii, H. A. and Kataoka, Y. and Katayama, I. and Kouwenhoven, W. and Langan, S. M. and Leshem, Y. A. and Merhand, S. and Mina-Osorio, P. and Murota, H. and Nakahara, T. and Nunes, F. P. and Nygaard, U. and Nygårdas, M. and Ohya, Y. and Ono, E. and Svensson, Å and von Kobyletzki, L.}},
issn = {{0007-0963}},
language = {{eng}},
month = {{05}},
number = {{5}},
pages = {{332--341}},
publisher = {{Wiley-Blackwell}},
series = {{British Journal of Dermatology}},
title = {{Report from the fifth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)}},
url = {{http://dx.doi.org/10.1111/bjd.16543}},
doi = {{10.1111/bjd.16543}},
volume = {{178}},
year = {{2018}},
}