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Lactic acid bacteria : From starter cultures to producers of chemicals

Hatti-Kaul, Rajni LU ; Chen, Lu LU ; Dishisha, Tarek LU and Enshasy, Hesham El (2018) In FEMS Microbiology Letters 365(20).
Abstract

Lactic acid bacteria constitute a diverse group of industrially significant, safe microorganisms that are primarily used as starter cultures and probiotics, and are also being developed as production systems in industrial biotechnology for biocatalysis and transformation of renewable feedstocks to commodity- and high-value chemicals, and health products. Development of strains, which was initially based mainly on natural approaches, is also achieved by metabolic engineering that has been facilitated by the availability of genome sequences and genetic tools for transformation of some of the bacterial strains. The aim of this paper is to provide a brief overview of the potential of lactic acid bacteria as biological catalysts for... (More)

Lactic acid bacteria constitute a diverse group of industrially significant, safe microorganisms that are primarily used as starter cultures and probiotics, and are also being developed as production systems in industrial biotechnology for biocatalysis and transformation of renewable feedstocks to commodity- and high-value chemicals, and health products. Development of strains, which was initially based mainly on natural approaches, is also achieved by metabolic engineering that has been facilitated by the availability of genome sequences and genetic tools for transformation of some of the bacterial strains. The aim of this paper is to provide a brief overview of the potential of lactic acid bacteria as biological catalysts for production of different organic compounds for food and non-food sectors based on their diversity, metabolicand stress tolerance features, as well as the use of genetic/metabolic engineering tools for enhancing their capabilities.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
biobased chemicals, biological catalysts, lactic acid bacteria, metabolic engineering, rerouting metabolism
in
FEMS Microbiology Letters
volume
365
issue
20
publisher
Elsevier
external identifiers
  • scopus:85054463815
ISSN
0378-1097
DOI
10.1093/femsle/fny213
language
English
LU publication?
yes
id
2c2ec9db-767a-494d-9d54-5eb367e20365
date added to LUP
2018-11-01 12:38:23
date last changed
2019-03-17 05:10:07
@article{2c2ec9db-767a-494d-9d54-5eb367e20365,
  abstract     = {<p>Lactic acid bacteria constitute a diverse group of industrially significant, safe microorganisms that are primarily used as starter cultures and probiotics, and are also being developed as production systems in industrial biotechnology for biocatalysis and transformation of renewable feedstocks to commodity- and high-value chemicals, and health products. Development of strains, which was initially based mainly on natural approaches, is also achieved by metabolic engineering that has been facilitated by the availability of genome sequences and genetic tools for transformation of some of the bacterial strains. The aim of this paper is to provide a brief overview of the potential of lactic acid bacteria as biological catalysts for production of different organic compounds for food and non-food sectors based on their diversity, metabolicand stress tolerance features, as well as the use of genetic/metabolic engineering tools for enhancing their capabilities.</p>},
  articleno    = {fny213},
  author       = {Hatti-Kaul, Rajni and Chen, Lu and Dishisha, Tarek and Enshasy, Hesham El},
  issn         = {0378-1097},
  keyword      = {biobased chemicals,biological catalysts,lactic acid bacteria,metabolic engineering,rerouting metabolism},
  language     = {eng},
  month        = {10},
  number       = {20},
  publisher    = {Elsevier},
  series       = {FEMS Microbiology Letters},
  title        = {Lactic acid bacteria : From starter cultures to producers of chemicals},
  url          = {http://dx.doi.org/10.1093/femsle/fny213},
  volume       = {365},
  year         = {2018},
}