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The reactivity of the back revisited. Are there differences in reactivity in different parts of the back?

Björk, Ann Kristin LU ; Bruze, Magnus LU ; Engfeldt, Malin LU ; Nielsen, Christel LU and Svedman, Cecilia LU (2017) In Contact Dermatitis 76(1). p.19-26
Abstract

Background: In the contact dermatitis literature, it is regularly stated that the patch test reactivity on various areas of the back differs; this might have a large impact on the reproducibility of patch testing. Objectives: To investigate the reproducibility of patch testing on the upper back with regard to the left as opposed to the right side and the medial as opposed to the lateral part of the upper back. The reproducibility over time and with regard to the reactivity pattern was also investigated. Methods: Thirty-one subjects with contact allergy to the metals gold (n=19) or nickel (n=12) were patch tested with serial dilutions, in triplicate applications, on different locations on the upper back. The Friedman test was used for... (More)

Background: In the contact dermatitis literature, it is regularly stated that the patch test reactivity on various areas of the back differs; this might have a large impact on the reproducibility of patch testing. Objectives: To investigate the reproducibility of patch testing on the upper back with regard to the left as opposed to the right side and the medial as opposed to the lateral part of the upper back. The reproducibility over time and with regard to the reactivity pattern was also investigated. Methods: Thirty-one subjects with contact allergy to the metals gold (n=19) or nickel (n=12) were patch tested with serial dilutions, in triplicate applications, on different locations on the upper back. The Friedman test was used for statistical calculations. Results: No significant differences in the reactivity of the back were found. In all gold-allergic patients and 11 of 12 nickel-allergic patients, the allergy could be reproduced with regard to previous patch testing, but the degree of reactivity differed. Conclusions: When a high level of standardization of the patch test technique with the same test system was used, there were no differences in patch test reactions and sites of application on the upper back.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Anatomical site, Angry back, Contact allergy, Excited skin syndrome, Patch test, Reactivity, Reproducibility, Serial dilution
in
Contact Dermatitis
volume
76
issue
1
pages
19 - 26
publisher
Federation of European Neuroscience Societies and Blackwell Publishing Ltd
external identifiers
  • scopus:84988569013
  • wos:000390785500003
ISSN
0105-1873
DOI
10.1111/cod.12657
language
English
LU publication?
yes
id
2d169406-fcc1-47b6-a6e2-2a7cd3fe8365
date added to LUP
2016-11-03 15:04:58
date last changed
2018-01-07 11:33:19
@article{2d169406-fcc1-47b6-a6e2-2a7cd3fe8365,
  abstract     = {<p>Background: In the contact dermatitis literature, it is regularly stated that the patch test reactivity on various areas of the back differs; this might have a large impact on the reproducibility of patch testing. Objectives: To investigate the reproducibility of patch testing on the upper back with regard to the left as opposed to the right side and the medial as opposed to the lateral part of the upper back. The reproducibility over time and with regard to the reactivity pattern was also investigated. Methods: Thirty-one subjects with contact allergy to the metals gold (n=19) or nickel (n=12) were patch tested with serial dilutions, in triplicate applications, on different locations on the upper back. The Friedman test was used for statistical calculations. Results: No significant differences in the reactivity of the back were found. In all gold-allergic patients and 11 of 12 nickel-allergic patients, the allergy could be reproduced with regard to previous patch testing, but the degree of reactivity differed. Conclusions: When a high level of standardization of the patch test technique with the same test system was used, there were no differences in patch test reactions and sites of application on the upper back.</p>},
  author       = {Björk, Ann Kristin and Bruze, Magnus and Engfeldt, Malin and Nielsen, Christel and Svedman, Cecilia},
  issn         = {0105-1873},
  keyword      = {Anatomical site,Angry back,Contact allergy,Excited skin syndrome,Patch test,Reactivity,Reproducibility,Serial dilution},
  language     = {eng},
  number       = {1},
  pages        = {19--26},
  publisher    = {Federation of European Neuroscience Societies and Blackwell Publishing Ltd},
  series       = {Contact Dermatitis},
  title        = {The reactivity of the back revisited. Are there differences in reactivity in different parts of the back?},
  url          = {http://dx.doi.org/10.1111/cod.12657},
  volume       = {76},
  year         = {2017},
}