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Coxsackievirus A6 and enterovirus 71 causing hand, foot and mouth disease in Cuba, 2011-2013

Fonseca, Magilé C; Sarmiento, Luis LU ; Resik, Sonia; Martínez, Yenisleidys; Hung, Lai Heng; Morier, Luis; Piñón, Alexander; Valdéz, Odalys; Kourí, Vivian and González, Guelsys (2014) In Archives of Virology 159(9). p.5-2451
Abstract

Hand, foot and mouth disease (HFMD) is usually caused by coxsackievirus A16 or enterovirus 71 (EV71). Between 2011 and 2013, HFMD cases were reported from different Cuban provinces. A total of 42 clinical specimens were obtained from 23 patients. Detection, identification and phylogenetic analysis of enterovirus-associated HFMD were carried out by virus isolation, specific enterovirus PCR and partial VP1 sequences. HEV was detected in 11 HFMD cases. Emerging genetic variants of coxsackievirus A6 and EV71 were identified as the causative agents of the Cuban HFMD cases.

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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adult, Child, Child, Preschool, Cluster Analysis, Cuba/epidemiology, Enterovirus/classification, Enterovirus A, Human/classification, Hand, Foot and Mouth Disease/epidemiology, Humans, Infant, Molecular Sequence Data, Phylogeny, RNA, Viral/genetics, Sequence Analysis, DNA, Sequence Homology, Viral Structural Proteins/genetics
in
Archives of Virology
volume
159
issue
9
pages
5 pages
publisher
Springer
external identifiers
  • scopus:84907865998
ISSN
1432-8798
DOI
10.1007/s00705-014-2071-x
language
English
LU publication?
no
id
2dab8ce1-cc37-4b7e-a147-f56d6ddf0f91
date added to LUP
2019-07-08 14:20:56
date last changed
2019-09-17 04:58:24
@article{2dab8ce1-cc37-4b7e-a147-f56d6ddf0f91,
  abstract     = {<p>Hand, foot and mouth disease (HFMD) is usually caused by coxsackievirus A16 or enterovirus 71 (EV71). Between 2011 and 2013, HFMD cases were reported from different Cuban provinces. A total of 42 clinical specimens were obtained from 23 patients. Detection, identification and phylogenetic analysis of enterovirus-associated HFMD were carried out by virus isolation, specific enterovirus PCR and partial VP1 sequences. HEV was detected in 11 HFMD cases. Emerging genetic variants of coxsackievirus A6 and EV71 were identified as the causative agents of the Cuban HFMD cases. </p>},
  author       = {Fonseca, Magilé C and Sarmiento, Luis and Resik, Sonia and Martínez, Yenisleidys and Hung, Lai Heng and Morier, Luis and Piñón, Alexander and Valdéz, Odalys and Kourí, Vivian and González, Guelsys},
  issn         = {1432-8798},
  keyword      = {Adult,Child,Child, Preschool,Cluster Analysis,Cuba/epidemiology,Enterovirus/classification,Enterovirus A, Human/classification,Hand, Foot and Mouth Disease/epidemiology,Humans,Infant,Molecular Sequence Data,Phylogeny,RNA, Viral/genetics,Sequence Analysis, DNA,Sequence Homology,Viral Structural Proteins/genetics},
  language     = {eng},
  number       = {9},
  pages        = {5--2451},
  publisher    = {Springer},
  series       = {Archives of Virology},
  title        = {Coxsackievirus A6 and enterovirus 71 causing hand, foot and mouth disease in Cuba, 2011-2013},
  url          = {http://dx.doi.org/10.1007/s00705-014-2071-x},
  volume       = {159},
  year         = {2014},
}