The benefits and drawbacks of home oxygen therapy for COPD : what’s next?
Khor, Yet H. and Ekström, Magnus LU
(2024)
In Expert Review of Respiratory Medicine
18(7).
p.469-483
- Abstract
Introduction: Home oxygen therapy is one of the few interventions that can improve survival in patients with chronic obstructive pulmonary disease (COPD) when administered appropriately, although it may cause side effects and be an unnecessary burden for some patients. Areas covered: This narrative review summarizes the current literature on the assessment of hypoxemia, different types of home oxygen therapy, potential beneficial and adverse effects, and emerging research on home oxygen therapy in COPD. A literature search was performed using MEDLINE and EMBASE up to January 2024, with additional articles being identified through clinical guidelines. Expert Opinion: Hypoxemia is common in patients with more severe COPD. Long-term oxygen... (More)
Introduction: Home oxygen therapy is one of the few interventions that can improve survival in patients with chronic obstructive pulmonary disease (COPD) when administered appropriately, although it may cause side effects and be an unnecessary burden for some patients. Areas covered: This narrative review summarizes the current literature on the assessment of hypoxemia, different types of home oxygen therapy, potential beneficial and adverse effects, and emerging research on home oxygen therapy in COPD. A literature search was performed using MEDLINE and EMBASE up to January 2024, with additional articles being identified through clinical guidelines. Expert Opinion: Hypoxemia is common in patients with more severe COPD. Long-term oxygen therapy is established to prolong survival in patients with chronic severe resting hypoxemia. Conversely, in the absence of chronic severe resting hypoxemia, home oxygen therapy has an unclear or conflicting evidence base, including for palliation of breathlessness, and is generally not recommended. However, beneficial effects in some patients cannot be precluded. Evidence is emerging on the optimal daily duration of oxygen use, the role of high-flow and auto-titrated oxygen therapy, improved informed decision-making, and telemonitoring. Further research is needed to validate novel oxygen delivery systems and monitoring tools and establish long-term effects of ambulatory oxygen therapy in COPD.
(Less)
- author
- Khor, Yet H.
and Ekström, Magnus
LU
- organization
- publishing date
- 2024
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- ambulatory care, Chronic obstructive pulmonary disease, hypoxemia, oximetry, oxygen therapy, respiratory failure
- in
- Expert Review of Respiratory Medicine
- volume
- 18
- issue
- 7
- pages
- 15 pages
- publisher
- Informa Healthcare
- external identifiers
-
- scopus:85198537732
- pmid:38984511
- ISSN
- 1747-6348
- DOI
- 10.1080/17476348.2024.2379459
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2024 Informa UK Limited, trading as Taylor & Francis Group.
- id
- 2ec7c39a-fd9c-4b42-a12a-6196807227b5
- date added to LUP
- 2024-12-04 11:48:59
- date last changed
- 2025-07-17 06:23:52
@article{2ec7c39a-fd9c-4b42-a12a-6196807227b5,
abstract = {{<p>Introduction: Home oxygen therapy is one of the few interventions that can improve survival in patients with chronic obstructive pulmonary disease (COPD) when administered appropriately, although it may cause side effects and be an unnecessary burden for some patients. Areas covered: This narrative review summarizes the current literature on the assessment of hypoxemia, different types of home oxygen therapy, potential beneficial and adverse effects, and emerging research on home oxygen therapy in COPD. A literature search was performed using MEDLINE and EMBASE up to January 2024, with additional articles being identified through clinical guidelines. Expert Opinion: Hypoxemia is common in patients with more severe COPD. Long-term oxygen therapy is established to prolong survival in patients with chronic severe resting hypoxemia. Conversely, in the absence of chronic severe resting hypoxemia, home oxygen therapy has an unclear or conflicting evidence base, including for palliation of breathlessness, and is generally not recommended. However, beneficial effects in some patients cannot be precluded. Evidence is emerging on the optimal daily duration of oxygen use, the role of high-flow and auto-titrated oxygen therapy, improved informed decision-making, and telemonitoring. Further research is needed to validate novel oxygen delivery systems and monitoring tools and establish long-term effects of ambulatory oxygen therapy in COPD.</p>}},
author = {{Khor, Yet H. and Ekström, Magnus}},
issn = {{1747-6348}},
keywords = {{ambulatory care; Chronic obstructive pulmonary disease; hypoxemia; oximetry; oxygen therapy; respiratory failure}},
language = {{eng}},
number = {{7}},
pages = {{469--483}},
publisher = {{Informa Healthcare}},
series = {{Expert Review of Respiratory Medicine}},
title = {{The benefits and drawbacks of home oxygen therapy for COPD : what’s next?}},
url = {{http://dx.doi.org/10.1080/17476348.2024.2379459}},
doi = {{10.1080/17476348.2024.2379459}},
volume = {{18}},
year = {{2024}},
}