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De zuigeling met een vitamine-K-deficiëntiebloeding ondanks adequate profylaxe

Van Hasselt, P. M. ; Houwen, R. H.J. ; Van Dijk, A. T.H. and De Koning, T. J. LU (2003) In Nederlands Tijdschrift voor Geneeskunde 147(16). p.737-740
Abstract

Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 μg the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had... (More)

Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 μg the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had occurred. In an infant with a bleeding tendency, one should consider the possibility of vitamin K deficiency, even if adequate prophylaxis has been given.

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author
; ; and
alternative title
Vitamin K deficiency bleeding in an infant despite adequate prophylaxis
publishing date
type
Contribution to journal
publication status
published
subject
in
Nederlands Tijdschrift voor Geneeskunde
volume
147
issue
16
pages
4 pages
publisher
Bohn Stafleu van Loghum
external identifiers
  • pmid:12731461
  • scopus:0037454413
ISSN
0028-2162
language
Dutch
LU publication?
no
id
2ec85b3e-a418-475f-9393-c4997e863039
date added to LUP
2020-03-03 19:09:22
date last changed
2020-09-23 08:07:11
@article{2ec85b3e-a418-475f-9393-c4997e863039,
  abstract     = {<p>Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 μg the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had occurred. In an infant with a bleeding tendency, one should consider the possibility of vitamin K deficiency, even if adequate prophylaxis has been given.</p>},
  author       = {Van Hasselt, P. M. and Houwen, R. H.J. and Van Dijk, A. T.H. and De Koning, T. J.},
  issn         = {0028-2162},
  language     = {mis},
  month        = {04},
  number       = {16},
  pages        = {737--740},
  publisher    = {Bohn Stafleu van Loghum},
  series       = {Nederlands Tijdschrift voor Geneeskunde},
  title        = {De zuigeling met een vitamine-K-deficiëntiebloeding ondanks adequate profylaxe},
  volume       = {147},
  year         = {2003},
}