De zuigeling met een vitamine-K-deficiëntiebloeding ondanks adequate profylaxe
(2003) In Nederlands Tijdschrift voor Geneeskunde 147(16). p.737-740- Abstract
Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 μg the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had... (More)
Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 μg the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had occurred. In an infant with a bleeding tendency, one should consider the possibility of vitamin K deficiency, even if adequate prophylaxis has been given.
(Less)
- author
- Van Hasselt, P. M. ; Houwen, R. H.J. ; Van Dijk, A. T.H. and De Koning, T. J. LU
- alternative title
- Vitamin K deficiency bleeding in an infant despite adequate prophylaxis
- publishing date
- 2003-04-19
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Nederlands Tijdschrift voor Geneeskunde
- volume
- 147
- issue
- 16
- pages
- 4 pages
- publisher
- Bohn Stafleu van Loghum
- external identifiers
-
- scopus:0037454413
- pmid:12731461
- ISSN
- 0028-2162
- language
- Dutch
- LU publication?
- no
- id
- 2ec85b3e-a418-475f-9393-c4997e863039
- date added to LUP
- 2020-03-03 19:09:22
- date last changed
- 2024-06-26 12:59:02
@article{2ec85b3e-a418-475f-9393-c4997e863039,
abstract = {{<p>Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 μg the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had occurred. In an infant with a bleeding tendency, one should consider the possibility of vitamin K deficiency, even if adequate prophylaxis has been given.</p>}},
author = {{Van Hasselt, P. M. and Houwen, R. H.J. and Van Dijk, A. T.H. and De Koning, T. J.}},
issn = {{0028-2162}},
language = {{mis}},
month = {{04}},
number = {{16}},
pages = {{737--740}},
publisher = {{Bohn Stafleu van Loghum}},
series = {{Nederlands Tijdschrift voor Geneeskunde}},
title = {{De zuigeling met een vitamine-K-deficiëntiebloeding ondanks adequate profylaxe}},
volume = {{147}},
year = {{2003}},
}