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Excess mortality by suicide in high-risk subgroups of suicide attempters: a prospective study of standardised mortality rates in suicide attempters examined at a medical emergency inpatient unit

Probert-Lindström, Sara LU orcid ; Öjehagen, Agneta LU ; Ambrus, Livia LU ; Skogman, Katarina LU and Berge, Jonas LU (2022) In BMJ Open 12. p.1-9
Abstract
Objectives The primary aim of the present study was to investigate the putative excess mortality by suicide in suicide attempters. As a secondary aim, we investigate excess mortality in specific, clinically relevant subgroups: individuals with repeated suicide attempts (RA); individuals who used violent method at the attempt (VA); and those who scored high on the Suicide Intent Scale (HS) at the time of the baseline attempt. Finally, we investigate excess mortality in men and women separately and within 5 years and over 5 years after hospital admission for attempted suicide.

Design Prospective register-based follow-up for 21–32 years. Standardised mortality ratio (SMR) was calculated for suicide using national census data.... (More)
Objectives The primary aim of the present study was to investigate the putative excess mortality by suicide in suicide attempters. As a secondary aim, we investigate excess mortality in specific, clinically relevant subgroups: individuals with repeated suicide attempts (RA); individuals who used violent method at the attempt (VA); and those who scored high on the Suicide Intent Scale (HS) at the time of the baseline attempt. Finally, we investigate excess mortality in men and women separately and within 5 years and over 5 years after hospital admission for attempted suicide.

Design Prospective register-based follow-up for 21–32 years. Standardised mortality ratio (SMR) was calculated for suicide using national census data. Clinically relevant subgroups were investigated separately.

Setting Medical emergency inpatient unit in the south of Sweden.

Participants 1039 individuals who were psychiatrically assessed at admission to medical inpatient care for attempted suicide between 1987 and 1998.

Outcome measure Suicide.

Results The overall SMR for suicide was 23.50 (95% CI 18.68 to 29.56); significantly higher (p<0.001) among women (30.49 (95% CI 22.27 to 41.72)) than men (18.61 (95% CI 13.30 to 26.05)). Mortality was highest within the first 5 years after the index suicide attempt (48.79 (95% CI 35.64 to 66.77)) compared with those who died after 5 years (p<0.001) (14.74 (10.53 to 20.63)). The highest independent SMR was found for VA (70.22 (95% CI 38.89 to 126.80)). In a regression model including RA, VA and HS all contributed significantly to excess suicide mortality.

Conclusions An elevated risk of premature death by suicide was found in suicide attempters compared with the general population. Assessment of previous suicide attempts is important, even though the attempt/s may have occurred decades ago. When assessing suicide risk, clinicians should consider repeated attempts and whether the attempts involved high suicidal intent and violent method. Healthcare interventions may benefit from targeting identified subgroups of attempters. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMJ Open
volume
12
article number
e054898
pages
1 - 9
publisher
BMJ Publishing Group
external identifiers
  • pmid:35623754
  • scopus:85131108070
ISSN
2044-6055
DOI
10.1136/bmjopen-2021-054898
language
English
LU publication?
yes
id
2edf334a-ba37-410d-a201-93db0f0fb053
date added to LUP
2022-05-27 15:59:46
date last changed
2023-06-14 04:00:56
@article{2edf334a-ba37-410d-a201-93db0f0fb053,
  abstract     = {{Objectives The primary aim of the present study was to investigate the putative excess mortality by suicide in suicide attempters. As a secondary aim, we investigate excess mortality in specific, clinically relevant subgroups: individuals with repeated suicide attempts (RA); individuals who used violent method at the attempt (VA); and those who scored high on the Suicide Intent Scale (HS) at the time of the baseline attempt. Finally, we investigate excess mortality in men and women separately and within 5 years and over 5 years after hospital admission for attempted suicide.<br/><br/>Design Prospective register-based follow-up for 21–32 years. Standardised mortality ratio (SMR) was calculated for suicide using national census data. Clinically relevant subgroups were investigated separately.<br/><br/>Setting Medical emergency inpatient unit in the south of Sweden.<br/><br/>Participants 1039 individuals who were psychiatrically assessed at admission to medical inpatient care for attempted suicide between 1987 and 1998.<br/><br/>Outcome measure Suicide.<br/><br/>Results The overall SMR for suicide was 23.50 (95% CI 18.68 to 29.56); significantly higher (p&lt;0.001) among women (30.49 (95% CI 22.27 to 41.72)) than men (18.61 (95% CI 13.30 to 26.05)). Mortality was highest within the first 5 years after the index suicide attempt (48.79 (95% CI 35.64 to 66.77)) compared with those who died after 5 years (p&lt;0.001) (14.74 (10.53 to 20.63)). The highest independent SMR was found for VA (70.22 (95% CI 38.89 to 126.80)). In a regression model including RA, VA and HS all contributed significantly to excess suicide mortality.<br/><br/>Conclusions An elevated risk of premature death by suicide was found in suicide attempters compared with the general population. Assessment of previous suicide attempts is important, even though the attempt/s may have occurred decades ago. When assessing suicide risk, clinicians should consider repeated attempts and whether the attempts involved high suicidal intent and violent method. Healthcare interventions may benefit from targeting identified subgroups of attempters.}},
  author       = {{Probert-Lindström, Sara and Öjehagen, Agneta and Ambrus, Livia and Skogman, Katarina and Berge, Jonas}},
  issn         = {{2044-6055}},
  language     = {{eng}},
  pages        = {{1--9}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{BMJ Open}},
  title        = {{Excess mortality by suicide in high-risk subgroups of suicide attempters: a prospective study of standardised mortality rates in suicide attempters examined at a medical emergency inpatient unit}},
  url          = {{http://dx.doi.org/10.1136/bmjopen-2021-054898}},
  doi          = {{10.1136/bmjopen-2021-054898}},
  volume       = {{12}},
  year         = {{2022}},
}