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Anorexia nervosa : 30-year outcome

Dobrescu, Sandra Rydberg ; DInkler, Lisa ; Gillberg, Carina I ; Råstam, Maria LU ; Gillberg, Christopher and Wentz, Elisabet (2020) In British Journal of Psychiatry 216(2). p.97-104
Abstract

Background Little is known about the long-term outcome of anorexia nervosa.Aims To study the 30-year outcome of adolescent-onset anorexia nervosa.Method All 4291 individuals born in 1970 and attending eighth grade in 1985 in Gothenburg, Sweden were screened for anorexia nervosa. A total of 24 individuals (age cohort for anorexia nervosa) were pooled with 27 individuals with anorexia nervosa (identified through community screening) who were born in 1969 and 1971-1974. The 51 individuals with anorexia nervosa and 51 school- and gender-matched controls were followed prospectively and examined at mean ages of 16, 21, 24, 32 and 44. Psychiatric disorders, health-related quality of life and general outcome were assessed.Results At the 30-year... (More)

Background Little is known about the long-term outcome of anorexia nervosa.Aims To study the 30-year outcome of adolescent-onset anorexia nervosa.Method All 4291 individuals born in 1970 and attending eighth grade in 1985 in Gothenburg, Sweden were screened for anorexia nervosa. A total of 24 individuals (age cohort for anorexia nervosa) were pooled with 27 individuals with anorexia nervosa (identified through community screening) who were born in 1969 and 1971-1974. The 51 individuals with anorexia nervosa and 51 school- and gender-matched controls were followed prospectively and examined at mean ages of 16, 21, 24, 32 and 44. Psychiatric disorders, health-related quality of life and general outcome were assessed.Results At the 30-year follow-up 96% of participants agreed to participate. There was no mortality. Of the participants, 19% had an eating disorder diagnosis (6% anorexia nervosa, 2% binge-eating disorder, 11% other specified feeding or eating disorder); 38% had other psychiatric diagnoses; and 64% had full eating disorder symptom recovery, i.e. free of all eating disorder criteria for 6 consecutive months. During the elapsed 30 years, participants had an eating disorder for 10 years, on average, and 23% did not receive psychiatric treatment. Good outcome was predicted by later age at onset among individuals with adolescent-onset anorexia nervosa and premorbid perfectionism.Conclusions This long-term follow-up study reflects the course of adolescent-onset anorexia nervosa and has shown a favourable outcome regarding mortality and full symptom recovery. However, one in five had a chronic eating disorder.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Anorexia nervosa, case-control, outcome, population based
in
British Journal of Psychiatry
volume
216
issue
2
pages
97 - 104
publisher
Royal College of Psychiatrists
external identifiers
  • pmid:31113504
  • scopus:85078724589
ISSN
0007-1250
DOI
10.1192/bjp.2019.113
language
English
LU publication?
yes
id
2ef04ead-85cc-4c55-9b41-f3f6d72e09da
date added to LUP
2020-02-14 16:10:23
date last changed
2020-02-26 07:41:51
@article{2ef04ead-85cc-4c55-9b41-f3f6d72e09da,
  abstract     = {<p>Background Little is known about the long-term outcome of anorexia nervosa.Aims To study the 30-year outcome of adolescent-onset anorexia nervosa.Method All 4291 individuals born in 1970 and attending eighth grade in 1985 in Gothenburg, Sweden were screened for anorexia nervosa. A total of 24 individuals (age cohort for anorexia nervosa) were pooled with 27 individuals with anorexia nervosa (identified through community screening) who were born in 1969 and 1971-1974. The 51 individuals with anorexia nervosa and 51 school- and gender-matched controls were followed prospectively and examined at mean ages of 16, 21, 24, 32 and 44. Psychiatric disorders, health-related quality of life and general outcome were assessed.Results At the 30-year follow-up 96% of participants agreed to participate. There was no mortality. Of the participants, 19% had an eating disorder diagnosis (6% anorexia nervosa, 2% binge-eating disorder, 11% other specified feeding or eating disorder); 38% had other psychiatric diagnoses; and 64% had full eating disorder symptom recovery, i.e. free of all eating disorder criteria for 6 consecutive months. During the elapsed 30 years, participants had an eating disorder for 10 years, on average, and 23% did not receive psychiatric treatment. Good outcome was predicted by later age at onset among individuals with adolescent-onset anorexia nervosa and premorbid perfectionism.Conclusions This long-term follow-up study reflects the course of adolescent-onset anorexia nervosa and has shown a favourable outcome regarding mortality and full symptom recovery. However, one in five had a chronic eating disorder.</p>},
  author       = {Dobrescu, Sandra Rydberg and DInkler, Lisa and Gillberg, Carina I and Råstam, Maria and Gillberg, Christopher and Wentz, Elisabet},
  issn         = {0007-1250},
  language     = {eng},
  number       = {2},
  pages        = {97--104},
  publisher    = {Royal College of Psychiatrists},
  series       = {British Journal of Psychiatry},
  title        = {Anorexia nervosa : 30-year outcome},
  url          = {http://dx.doi.org/10.1192/bjp.2019.113},
  doi          = {10.1192/bjp.2019.113},
  volume       = {216},
  year         = {2020},
}