Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Contact Allergy to Oxidized Linalool and Oxidized Limonene is Over-represented in Individuals with Photocontact Allergy to Ketoprofen

Bruze, Magnus LU ; Marmgren, Victoria LU ; Antelmi, Annarita LU ; Hindsén Stenström, Monica LU ; Svedman, Cecilia LU ; Zimersson, Erik and Mowitz, Martin LU (2021) In Acta Dermato-Venereologica 101(5).
Abstract

Simultaneous contact allergies are common in individuals with photocontact allergy to ketoprofen. The rate of contact allergy to the fragrance substances oxidized linalool and oxidized limonene in ketoprofen-photo-allergic individuals were investigated in comparison with the corresponding rates in individuals without photo-contact allergy to ketoprofen, using Fisher's exact test. A total of 4,021 patients were routinely tested with oxidized linalool; of whom 190 (4.7%) tested positively. For oxidized limonene the numbers were 3,797 patients and 111 positive reactions (2.9%). A total of 19 contact allergic reactions to oxidized linalool were noted in 29 patients (65.5%) who also had photocontact allergy to ketoprofen (p < 0.0001). The... (More)

Simultaneous contact allergies are common in individuals with photocontact allergy to ketoprofen. The rate of contact allergy to the fragrance substances oxidized linalool and oxidized limonene in ketoprofen-photo-allergic individuals were investigated in comparison with the corresponding rates in individuals without photo-contact allergy to ketoprofen, using Fisher's exact test. A total of 4,021 patients were routinely tested with oxidized linalool; of whom 190 (4.7%) tested positively. For oxidized limonene the numbers were 3,797 patients and 111 positive reactions (2.9%). A total of 19 contact allergic reactions to oxidized linalool were noted in 29 patients (65.5%) who also had photocontact allergy to ketoprofen (p < 0.0001). The corresponding figures for oxidized limonene were 10 positive reactions in 24 ketoprofen-photoallergic individuals (41.7%) (p < 0.0001). Contact allergy to oxidized linalool and/or oxidized limonene is common in routinely tested patients with dermatitis and, particularly, in those patients who are photoallergic to ketoprofen.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
delayedhypersensitivity, fragrance substance, oxidation, patch-testing, photoallergic, photopatch-testing, photosensitizer, allergic contact dermatitis
in
Acta Dermato-Venereologica
volume
101
issue
5
article number
adv00454
publisher
Medical Journals Limited
external identifiers
  • pmid:33846762
  • scopus:85106667244
ISSN
1651-2057
DOI
10.2340/00015555-3799
language
English
LU publication?
yes
id
2f8529f5-d5a2-464f-a702-c5c76bfcedda
date added to LUP
2021-06-08 16:14:42
date last changed
2025-01-26 11:24:49
@article{2f8529f5-d5a2-464f-a702-c5c76bfcedda,
  abstract     = {{<p>Simultaneous contact allergies are common in individuals with photocontact allergy to ketoprofen. The rate of contact allergy to the fragrance substances oxidized linalool and oxidized limonene in ketoprofen-photo-allergic individuals were investigated in comparison with the corresponding rates in individuals without photo-contact allergy to ketoprofen, using Fisher's exact test. A total of 4,021 patients were routinely tested with oxidized linalool; of whom 190 (4.7%) tested positively. For oxidized limonene the numbers were 3,797 patients and 111 positive reactions (2.9%). A total of 19 contact allergic reactions to oxidized linalool were noted in 29 patients (65.5%) who also had photocontact allergy to ketoprofen (p &lt; 0.0001). The corresponding figures for oxidized limonene were 10 positive reactions in 24 ketoprofen-photoallergic individuals (41.7%) (p &lt; 0.0001). Contact allergy to oxidized linalool and/or oxidized limonene is common in routinely tested patients with dermatitis and, particularly, in those patients who are photoallergic to ketoprofen.</p>}},
  author       = {{Bruze, Magnus and Marmgren, Victoria and Antelmi, Annarita and Hindsén Stenström, Monica and Svedman, Cecilia and Zimersson, Erik and Mowitz, Martin}},
  issn         = {{1651-2057}},
  keywords     = {{delayedhypersensitivity; fragrance substance; oxidation; patch-testing; photoallergic; photopatch-testing; photosensitizer; allergic contact dermatitis}},
  language     = {{eng}},
  month        = {{05}},
  number       = {{5}},
  publisher    = {{Medical Journals Limited}},
  series       = {{Acta Dermato-Venereologica}},
  title        = {{Contact Allergy to Oxidized Linalool and Oxidized Limonene is Over-represented in Individuals with Photocontact Allergy to Ketoprofen}},
  url          = {{http://dx.doi.org/10.2340/00015555-3799}},
  doi          = {{10.2340/00015555-3799}},
  volume       = {{101}},
  year         = {{2021}},
}