Incidence and prevalence of giant cell arteritis and polymyalgia rheumatica : A systematic literature review
(2020) In Seminars in Arthritis and Rheumatism 50(5). p.1040-1048- Abstract
Background: Giant cell arteritis (GCA; sometimes referred to as temporal arteritis) and polymyalgia rheumatica (PMR) are common and interrelated inflammatory conditions that almost exclusively affect adults older than 50 years. There is a need for updated information on the epidemiology of these diseases. Objective: This systematic literature review (SLR) aims to summarize current evidence regarding the global incidence and prevalence of GCA and PMR. Methodology: A systematic search of PubMed and Google Scholar databases from their inception dates to July 30, 2019 for relevant publications was performed. Studies that reported incidence and/or prevalence estimates for GCA and/or PMR were identified. When there were multiple studies of... (More)
Background: Giant cell arteritis (GCA; sometimes referred to as temporal arteritis) and polymyalgia rheumatica (PMR) are common and interrelated inflammatory conditions that almost exclusively affect adults older than 50 years. There is a need for updated information on the epidemiology of these diseases. Objective: This systematic literature review (SLR) aims to summarize current evidence regarding the global incidence and prevalence of GCA and PMR. Methodology: A systematic search of PubMed and Google Scholar databases from their inception dates to July 30, 2019 for relevant publications was performed. Studies that reported incidence and/or prevalence estimates for GCA and/or PMR were identified. When there were multiple studies of the same population, the most recent estimates were used. Details on source populations and case validation were systematically reviewed. Results were tabulated per region in the world. Results: Screening by 2 authors resulted in 2643 abstracts, of which 77 articles met the inclusion criteria. There were more studies on GCA compared to PMR, and more on incidence than on prevalence. Wide variations were found in study design and populations studied. Studies that included a thorough case validation tended to give lower estimates, in particular for PMR. The highest incidence per 100 000 aged ≥50 years of GCA was observed in studies from Scandinavia and the UK (14.6 to 43.6), and in Minnesota, USA (19.8 per 100 000). Corresponding estimates for Southern Europe were lower (1.1 to 11.1). Limited evidence indicates that GCA and PMR is less common in non-Caucasian populations. Prevalence estimates for PMR were ≥ 3 times higher than that of GCA in Caucasians. Conclusion: This SLR provides up to date estimates of the occurrence of GCA and PMR in different populations around the world. The incidence of GCA is higher in populations of Northern European ancestry. Data on the epidemiology of PMR are more limited, with greater variation in incidence and prevalence estimates.
(Less)
- author
- Sharma, Ankita LU ; Mohammad, Aladdin LU and Turesson, Carl LU
- organization
- publishing date
- 2020-10-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Seminars in Arthritis and Rheumatism
- volume
- 50
- issue
- 5
- pages
- 9 pages
- publisher
- W.B. Saunders
- external identifiers
-
- pmid:32911281
- scopus:85090366024
- ISSN
- 0049-0172
- DOI
- 10.1016/j.semarthrit.2020.07.005
- language
- English
- LU publication?
- yes
- id
- 2ffae5ea-0d76-4b4d-b963-3eec914a210d
- date added to LUP
- 2020-09-30 15:00:55
- date last changed
- 2024-05-02 15:56:14
@article{2ffae5ea-0d76-4b4d-b963-3eec914a210d,
abstract = {{<p>Background: Giant cell arteritis (GCA; sometimes referred to as temporal arteritis) and polymyalgia rheumatica (PMR) are common and interrelated inflammatory conditions that almost exclusively affect adults older than 50 years. There is a need for updated information on the epidemiology of these diseases. Objective: This systematic literature review (SLR) aims to summarize current evidence regarding the global incidence and prevalence of GCA and PMR. Methodology: A systematic search of PubMed and Google Scholar databases from their inception dates to July 30, 2019 for relevant publications was performed. Studies that reported incidence and/or prevalence estimates for GCA and/or PMR were identified. When there were multiple studies of the same population, the most recent estimates were used. Details on source populations and case validation were systematically reviewed. Results were tabulated per region in the world. Results: Screening by 2 authors resulted in 2643 abstracts, of which 77 articles met the inclusion criteria. There were more studies on GCA compared to PMR, and more on incidence than on prevalence. Wide variations were found in study design and populations studied. Studies that included a thorough case validation tended to give lower estimates, in particular for PMR. The highest incidence per 100 000 aged ≥50 years of GCA was observed in studies from Scandinavia and the UK (14.6 to 43.6), and in Minnesota, USA (19.8 per 100 000). Corresponding estimates for Southern Europe were lower (1.1 to 11.1). Limited evidence indicates that GCA and PMR is less common in non-Caucasian populations. Prevalence estimates for PMR were ≥ 3 times higher than that of GCA in Caucasians. Conclusion: This SLR provides up to date estimates of the occurrence of GCA and PMR in different populations around the world. The incidence of GCA is higher in populations of Northern European ancestry. Data on the epidemiology of PMR are more limited, with greater variation in incidence and prevalence estimates.</p>}},
author = {{Sharma, Ankita and Mohammad, Aladdin and Turesson, Carl}},
issn = {{0049-0172}},
language = {{eng}},
month = {{10}},
number = {{5}},
pages = {{1040--1048}},
publisher = {{W.B. Saunders}},
series = {{Seminars in Arthritis and Rheumatism}},
title = {{Incidence and prevalence of giant cell arteritis and polymyalgia rheumatica : A systematic literature review}},
url = {{http://dx.doi.org/10.1016/j.semarthrit.2020.07.005}},
doi = {{10.1016/j.semarthrit.2020.07.005}},
volume = {{50}},
year = {{2020}},
}