Familial risk of sleep-disordered breathing
(2012) In Sleep Medicine 13(6). p.668-673- Abstract
- Objective: To estimate the incidence of hospitalization for paediatric obstructive sleep apnoea syndrome (OSAS) or sleep-disordered breathing (SDB) caused by adenotonsillar or tonsillar hypertrophy without infection in children with a parent affected by OSAS. Patients and methods: Using the MigMed database at Lund University, hospital data on all children aged 0-18 years in Sweden between 1997 and 2007 (total of 3 million individuals) were used to identify all first hospital admissions for OSAS or either adenotonsillar or tonsillar hypertrophy. Next, individuals were categorized as either having or not having a parent affected by OSAS. Standardized incidence ratios (SIRs) with 95% confidence intervals (CIs) were estimated for boys and... (More)
- Objective: To estimate the incidence of hospitalization for paediatric obstructive sleep apnoea syndrome (OSAS) or sleep-disordered breathing (SDB) caused by adenotonsillar or tonsillar hypertrophy without infection in children with a parent affected by OSAS. Patients and methods: Using the MigMed database at Lund University, hospital data on all children aged 0-18 years in Sweden between 1997 and 2007 (total of 3 million individuals) were used to identify all first hospital admissions for OSAS or either adenotonsillar or tonsillar hypertrophy. Next, individuals were categorized as either having or not having a parent affected by OSAS. Standardized incidence ratios (SIRs) with 95% confidence intervals (CIs) were estimated for boys and girls with a parent affected by OSAS. Children with OSAS or adenotonsillar or tonsillar hypertrophy without a parent affected by OSAS acted as the reference group (SIR = 1). Results: After accounting for socio-economic status, age, and geographic region, the SIRs of OSAS in boys and girls with a parent affected by OSAS were 3.09 (95% CI 1.83-4.90) and 4.46 (95% CI 2.68-6.98), respectively. The SIRs of adenotonsillar or tonsillar hypertrophy in boys and girls with a parent affected by OSAS were 1.82 (95% CI 1.54-2.14) and 1.56 (95% CI 1.30-1.87), respectively. Conclusion: This study indicates familial clustering of sleep-disordered breathing, which is important information for clinicians. (C) 2012 Elsevier B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3001258
- author
- Lundkvist, Karin ; Sundquist, Kristina LU ; Li, Xinjun LU and Friberg, Danielle
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adenotonsillar hypertrophy, Children, Heredity, Hospitalization, Obstructive sleep apnoea, Population-based studies, Sleep-disordered, breathing
- in
- Sleep Medicine
- volume
- 13
- issue
- 6
- pages
- 668 - 673
- publisher
- Elsevier
- external identifiers
-
- wos:000306304700019
- scopus:84861925956
- pmid:22538192
- ISSN
- 1878-5506
- DOI
- 10.1016/j.sleep.2012.01.014
- language
- English
- LU publication?
- yes
- id
- 977ded8f-abe4-47fd-baeb-e6278d525acf (old id 3001258)
- date added to LUP
- 2016-04-01 10:53:39
- date last changed
- 2022-01-26 03:34:32
@article{977ded8f-abe4-47fd-baeb-e6278d525acf, abstract = {{Objective: To estimate the incidence of hospitalization for paediatric obstructive sleep apnoea syndrome (OSAS) or sleep-disordered breathing (SDB) caused by adenotonsillar or tonsillar hypertrophy without infection in children with a parent affected by OSAS. Patients and methods: Using the MigMed database at Lund University, hospital data on all children aged 0-18 years in Sweden between 1997 and 2007 (total of 3 million individuals) were used to identify all first hospital admissions for OSAS or either adenotonsillar or tonsillar hypertrophy. Next, individuals were categorized as either having or not having a parent affected by OSAS. Standardized incidence ratios (SIRs) with 95% confidence intervals (CIs) were estimated for boys and girls with a parent affected by OSAS. Children with OSAS or adenotonsillar or tonsillar hypertrophy without a parent affected by OSAS acted as the reference group (SIR = 1). Results: After accounting for socio-economic status, age, and geographic region, the SIRs of OSAS in boys and girls with a parent affected by OSAS were 3.09 (95% CI 1.83-4.90) and 4.46 (95% CI 2.68-6.98), respectively. The SIRs of adenotonsillar or tonsillar hypertrophy in boys and girls with a parent affected by OSAS were 1.82 (95% CI 1.54-2.14) and 1.56 (95% CI 1.30-1.87), respectively. Conclusion: This study indicates familial clustering of sleep-disordered breathing, which is important information for clinicians. (C) 2012 Elsevier B.V. All rights reserved.}}, author = {{Lundkvist, Karin and Sundquist, Kristina and Li, Xinjun and Friberg, Danielle}}, issn = {{1878-5506}}, keywords = {{Adenotonsillar hypertrophy; Children; Heredity; Hospitalization; Obstructive sleep apnoea; Population-based studies; Sleep-disordered; breathing}}, language = {{eng}}, number = {{6}}, pages = {{668--673}}, publisher = {{Elsevier}}, series = {{Sleep Medicine}}, title = {{Familial risk of sleep-disordered breathing}}, url = {{https://lup.lub.lu.se/search/files/2214192/3124955.pdf}}, doi = {{10.1016/j.sleep.2012.01.014}}, volume = {{13}}, year = {{2012}}, }