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Compensatory endocytosis in chromaffin cells

Barg, Sebastian LU and Machado, J. D. (2007) In Acta Physiologica 192(2). p.195-201
Abstract
Exocytosis occurs via fusion of secretory granules with the cell membrane, whereupon the granule content is at least partially released and the granule membrane is temporarily added to the plasma membrane. Exocytosis is balanced by compensatory endocytosis to achieve net equilibrium of the cell surface area and to recycle and redistribute components of the exocytosis machinery. The underlying molecular mechanisms remain a matter of debate. In this review, we will summarize and discuss recent progress in the understanding of compensatory endocytosis, with the focus on chromaffin cells as a useful model for studying mechanisms of regulated secretion.
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
capacitance, clathrin, dynamin, exocytosis, fluorescence microscopy, secretion
in
Acta Physiologica
volume
192
issue
2
pages
195 - 201
publisher
Wiley-Blackwell
external identifiers
  • pmid:18021324
  • scopus:38549087820
  • pmid:18021324
ISSN
1748-1708
DOI
10.1111/j.1748-1716.2007.01813.x
language
English
LU publication?
yes
id
3006ec3d-4093-430a-a868-ac42d39bc08d (old id 1139614)
date added to LUP
2016-04-01 12:29:07
date last changed
2022-01-27 05:43:12
@article{3006ec3d-4093-430a-a868-ac42d39bc08d,
  abstract     = {{Exocytosis occurs via fusion of secretory granules with the cell membrane, whereupon the granule content is at least partially released and the granule membrane is temporarily added to the plasma membrane. Exocytosis is balanced by compensatory endocytosis to achieve net equilibrium of the cell surface area and to recycle and redistribute components of the exocytosis machinery. The underlying molecular mechanisms remain a matter of debate. In this review, we will summarize and discuss recent progress in the understanding of compensatory endocytosis, with the focus on chromaffin cells as a useful model for studying mechanisms of regulated secretion.}},
  author       = {{Barg, Sebastian and Machado, J. D.}},
  issn         = {{1748-1708}},
  keywords     = {{capacitance; clathrin; dynamin; exocytosis; fluorescence microscopy; secretion}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{195--201}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Physiologica}},
  title        = {{Compensatory endocytosis in chromaffin cells}},
  url          = {{http://dx.doi.org/10.1111/j.1748-1716.2007.01813.x}},
  doi          = {{10.1111/j.1748-1716.2007.01813.x}},
  volume       = {{192}},
  year         = {{2007}},
}