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Decrease of 7T MR short-term effects with repeated exposure

Hansson, Boel LU ; Garzón, Benjamín ; Lövdén, Martin and Björkman-Burtscher, Isabella M. LU (2024) In Neuroradiology
Abstract

Purpose: Although participants in 7 T magnetic resonance (MR) studies tolerate ultra-high field (UHF) well, subjectively experienced short-term effects, such as dizziness, inconsistent movement, nausea, or metallic taste, are reported. Evidence on subjectively experienced short-term effects in multiple exposures to UHF MR is scarce. The purpose of this study is to investigated experience of short-term effects, and occurrence of motion in healthy subjects exposed to seven weekly 7 T MR examinations. Methods: A questionnaire on short-term effects was completed by participants in an fMRI motor skill study. Seven UHF MR examinations were conducted over 7 weeks (exposure number: 1 to 7). Changes of experienced short-term effects were... (More)

Purpose: Although participants in 7 T magnetic resonance (MR) studies tolerate ultra-high field (UHF) well, subjectively experienced short-term effects, such as dizziness, inconsistent movement, nausea, or metallic taste, are reported. Evidence on subjectively experienced short-term effects in multiple exposures to UHF MR is scarce. The purpose of this study is to investigated experience of short-term effects, and occurrence of motion in healthy subjects exposed to seven weekly 7 T MR examinations. Methods: A questionnaire on short-term effects was completed by participants in an fMRI motor skill study. Seven UHF MR examinations were conducted over 7 weeks (exposure number: 1 to 7). Changes of experienced short-term effects were analyzed. Motion in fMRI images was quantified. Results: The questionnaire was completed 360 times by 67 participants after one to seven 7T MR examinations. Logistic mixed model analysis showed a significant association between dizziness, inconsistent movement, nausea, and headache and the examination numbers (p<0.03). Exposure to repeated examinations had no significant effect on peripheral nerve stimulation (PNS) or motion of the subjects. The overall experience of a 7T examination improved significantly (p<0.001) with increasing examination numbers. Conclusion: During multiple 7T examinations, subjects adapt to the strong static field. The short-term effects dizziness, inconsistent movement, nausea, and headache decrease over time as the MR sessions continue and experienced comfort increases. There was no significant difference in motion during the multiple fMRI examinations.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Adaptation, Biological, Dizziness, Magnetic resonance imaging, Nausea
in
Neuroradiology
publisher
Springer
external identifiers
  • pmid:38270624
  • scopus:85183050790
ISSN
0028-3940
DOI
10.1007/s00234-024-03292-4
language
English
LU publication?
yes
id
300af6dc-f3a0-436b-a595-38e93e3d4217
date added to LUP
2024-02-20 12:42:42
date last changed
2024-04-23 16:11:22
@article{300af6dc-f3a0-436b-a595-38e93e3d4217,
  abstract     = {{<p>Purpose: Although participants in 7 T magnetic resonance (MR) studies tolerate ultra-high field (UHF) well, subjectively experienced short-term effects, such as dizziness, inconsistent movement, nausea, or metallic taste, are reported. Evidence on subjectively experienced short-term effects in multiple exposures to UHF MR is scarce. The purpose of this study is to investigated experience of short-term effects, and occurrence of motion in healthy subjects exposed to seven weekly 7 T MR examinations. Methods: A questionnaire on short-term effects was completed by participants in an fMRI motor skill study. Seven UHF MR examinations were conducted over 7 weeks (exposure number: 1 to 7). Changes of experienced short-term effects were analyzed. Motion in fMRI images was quantified. Results: The questionnaire was completed 360 times by 67 participants after one to seven 7T MR examinations. Logistic mixed model analysis showed a significant association between dizziness, inconsistent movement, nausea, and headache and the examination numbers (p&lt;0.03). Exposure to repeated examinations had no significant effect on peripheral nerve stimulation (PNS) or motion of the subjects. The overall experience of a 7T examination improved significantly (p&lt;0.001) with increasing examination numbers. Conclusion: During multiple 7T examinations, subjects adapt to the strong static field. The short-term effects dizziness, inconsistent movement, nausea, and headache decrease over time as the MR sessions continue and experienced comfort increases. There was no significant difference in motion during the multiple fMRI examinations.</p>}},
  author       = {{Hansson, Boel and Garzón, Benjamín and Lövdén, Martin and Björkman-Burtscher, Isabella M.}},
  issn         = {{0028-3940}},
  keywords     = {{Adaptation; Biological; Dizziness; Magnetic resonance imaging; Nausea}},
  language     = {{eng}},
  publisher    = {{Springer}},
  series       = {{Neuroradiology}},
  title        = {{Decrease of 7T MR short-term effects with repeated exposure}},
  url          = {{http://dx.doi.org/10.1007/s00234-024-03292-4}},
  doi          = {{10.1007/s00234-024-03292-4}},
  year         = {{2024}},
}