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Monte Carlo simulations of Donnan equilibrium in cartilage

Algotsson, Jenny LU ; Åkesson, Torbjörn LU and Forsman, Jan LU (2012) In Magnetic Resonance in Medicine 68(4). p.1298-1302
Abstract
(23) Na magnetic resonance imaging and the delayed gadolinium-enhanced magnetic resonance imaging methods to investigate cartilage can be used to determine the fixed charge density of cartilage. The methods give results that differ by a factor of 2. In this study, we use Monte Carlo simulations on a model system of cartilage and find that the difference originates from the Coulombic intermolecular interactions between the ions in the cartilage, and in the synovial fluid. Those interactions are neglected in the standard Donnan analysis that generally is adopted to evaluate magnetic resonance imaging data. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Magnetic Resonance in Medicine
volume
68
issue
4
pages
1298 - 1302
publisher
Wiley Online Library
external identifiers
  • wos:000309203500035
  • pmid:22890897
  • scopus:84866730524
ISSN
1522-2594
DOI
10.1002/mrm.24409
language
English
LU publication?
yes
id
48b030f7-fe7a-4785-b918-d46fce662cfd (old id 3047522)
date added to LUP
2012-09-10 15:11:19
date last changed
2017-01-08 03:39:48
@article{48b030f7-fe7a-4785-b918-d46fce662cfd,
  abstract     = {(23) Na magnetic resonance imaging and the delayed gadolinium-enhanced magnetic resonance imaging methods to investigate cartilage can be used to determine the fixed charge density of cartilage. The methods give results that differ by a factor of 2. In this study, we use Monte Carlo simulations on a model system of cartilage and find that the difference originates from the Coulombic intermolecular interactions between the ions in the cartilage, and in the synovial fluid. Those interactions are neglected in the standard Donnan analysis that generally is adopted to evaluate magnetic resonance imaging data. Magn Reson Med, 2012. © 2012 Wiley Periodicals, Inc.},
  author       = {Algotsson, Jenny and Åkesson, Torbjörn and Forsman, Jan},
  issn         = {1522-2594},
  language     = {eng},
  number       = {4},
  pages        = {1298--1302},
  publisher    = {Wiley Online Library},
  series       = {Magnetic Resonance in Medicine},
  title        = {Monte Carlo simulations of Donnan equilibrium in cartilage},
  url          = {http://dx.doi.org/10.1002/mrm.24409},
  volume       = {68},
  year         = {2012},
}