Advanced

Sex differences in lung vulnerability to tobacco smoking

Langhammer, A; Johnsen, R; Gulsvik, A; Holmen, TL and Bjermer, Leif LU (2003) In European Respiratory Journal1988-01-01+01:00 21(6). p.1017-1023
Abstract
Studies have indicated that females are more vulnerable to the deleterious effect of tobacco smoking than males. The current study aimed to investigate the associations between tobacco smoking and reported respiratory symptoms, self-rated health, and lung function by sex. In 1995-1997 65,225 subjects aged greater than or equal to 20 yrs (71% of invited) attended for screening within the Nord-Trondelag Health Study. Among these, 10,941 subjects selected randomly or because they reported having asthma or asthma-related symptoms, participated in the Bronchial Obstruction in Nord-Trondelag study consisting of spirometry and a personal interview. Tobacco smoking was associated with increased prevalence of respiratory symptoms, reduced lung... (More)
Studies have indicated that females are more vulnerable to the deleterious effect of tobacco smoking than males. The current study aimed to investigate the associations between tobacco smoking and reported respiratory symptoms, self-rated health, and lung function by sex. In 1995-1997 65,225 subjects aged greater than or equal to 20 yrs (71% of invited) attended for screening within the Nord-Trondelag Health Study. Among these, 10,941 subjects selected randomly or because they reported having asthma or asthma-related symptoms, participated in the Bronchial Obstruction in Nord-Trondelag study consisting of spirometry and a personal interview. Tobacco smoking was associated with increased prevalence of respiratory symptoms, reduced lung function, and lower score on global self-rated health (SRH). Adjusted for smoking burden and lung function, females had a higher risk for reporting respiratory symptoms and lower SRH compared with males. Further, smoking burden was associated with a larger relative reduction in expiratory lung function in females than in males. Females reported more symptoms and lower self-rated health compared with males with similar smoking burden. Even if smoking in females was associated with a larger reduction in per cent predicted lung function compared with males, this does not fully explain the higher symptom prevalence in females. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
lung function, self-rated health, sex, tobacco, smoking, respiratory symptoms
in
European Respiratory Journal1988-01-01+01:00
volume
21
issue
6
pages
1017 - 1023
publisher
Eur Respiratory Soc
external identifiers
  • wos:000183242900019
  • pmid:12797498
  • scopus:0037637606
ISSN
1399-3003
DOI
10.1183/09031936.03.00053202
language
English
LU publication?
yes
id
de0f9583-abe2-48e1-9e4c-d87be630ed98 (old id 309613)
alternative location
http://www.erj.ersjournals.com/cgi/content/abstract/21/6/1017
date added to LUP
2007-09-16 11:25:04
date last changed
2018-02-18 03:40:59
@article{de0f9583-abe2-48e1-9e4c-d87be630ed98,
  abstract     = {Studies have indicated that females are more vulnerable to the deleterious effect of tobacco smoking than males. The current study aimed to investigate the associations between tobacco smoking and reported respiratory symptoms, self-rated health, and lung function by sex. In 1995-1997 65,225 subjects aged greater than or equal to 20 yrs (71% of invited) attended for screening within the Nord-Trondelag Health Study. Among these, 10,941 subjects selected randomly or because they reported having asthma or asthma-related symptoms, participated in the Bronchial Obstruction in Nord-Trondelag study consisting of spirometry and a personal interview. Tobacco smoking was associated with increased prevalence of respiratory symptoms, reduced lung function, and lower score on global self-rated health (SRH). Adjusted for smoking burden and lung function, females had a higher risk for reporting respiratory symptoms and lower SRH compared with males. Further, smoking burden was associated with a larger relative reduction in expiratory lung function in females than in males. Females reported more symptoms and lower self-rated health compared with males with similar smoking burden. Even if smoking in females was associated with a larger reduction in per cent predicted lung function compared with males, this does not fully explain the higher symptom prevalence in females.},
  author       = {Langhammer, A and Johnsen, R and Gulsvik, A and Holmen, TL and Bjermer, Leif},
  issn         = {1399-3003},
  keyword      = {lung function,self-rated health,sex,tobacco,smoking,respiratory symptoms},
  language     = {eng},
  number       = {6},
  pages        = {1017--1023},
  publisher    = {Eur Respiratory Soc},
  series       = {European Respiratory Journal1988-01-01+01:00},
  title        = {Sex differences in lung vulnerability to tobacco smoking},
  url          = {http://dx.doi.org/10.1183/09031936.03.00053202},
  volume       = {21},
  year         = {2003},
}