A link between Helicobacter pylori and/or Chlamydia spp. infections and atherosclerosis
(2003) In Pathogens and Disease 36(3). p.187-192- Abstract
- Antibodies to Helicobacter pylori, Chlamydia spp. and Mycobacterium bovis were determined in patients with coronary heart disease, H. pylori-related dyspepsia, and tuberculosis, and healthy controls. Enzyme-linked immunosorbent assay was conducted with a glycine extract and CagA protein of H. pylori, chlamydial lipopolysaccharide and mycobacterial heat shock protein Hsp65. The prevalence of anti-glycine extract IgG in coronary heart disease patients was higher than in the tuberculosis group and controls, and the same as in dyspeptic patients. Anti-chlamydial IgG were more prevalent in the coronary heart disease group than in healthy subjects. There was no difference in the prevalence of anti-CagA IgG in the coronary heart disease group and... (More)
- Antibodies to Helicobacter pylori, Chlamydia spp. and Mycobacterium bovis were determined in patients with coronary heart disease, H. pylori-related dyspepsia, and tuberculosis, and healthy controls. Enzyme-linked immunosorbent assay was conducted with a glycine extract and CagA protein of H. pylori, chlamydial lipopolysaccharide and mycobacterial heat shock protein Hsp65. The prevalence of anti-glycine extract IgG in coronary heart disease patients was higher than in the tuberculosis group and controls, and the same as in dyspeptic patients. Anti-chlamydial IgG were more prevalent in the coronary heart disease group than in healthy subjects. There was no difference in the prevalence of anti-CagA IgG in the coronary heart disease group and controls or anti-Hsp65 IgG in the patients with coronary heart disease, dyspepsia, tuberculosis, and controls. Anti-glycine extract IgA (like anti-glycine extract IgG) were more prevalent in the coronary heart disease group than in the healthy group. The highest anti-glycine extract IgG/IgA and anti-chlamydial IgG titers were more frequent in coronary heart disease patients as compared with controls. Infections with H. pylori and Chlamydia spp. and enhanced production of antibodies to these pathogens may predispose to human atherosclerosis. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/310909
- author
- Chmiela, Magdalena ; Kowlewicz-Kulbat, Magdalena ; Miszczak, Aneta ; Wisniewska, Monika ; Rechcinski, Tomasz ; Kolodziej, Katarzyna ; Kasprzak, Jaroslaw ; Wadström, Torkel LU and Rudnicka, Wieslawa
- organization
- publishing date
- 2003
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Helicobacter pylori, Chlamydia spp., atherosclerosis
- in
- Pathogens and Disease
- volume
- 36
- issue
- 3
- pages
- 187 - 192
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000182940400012
- pmid:12738390
- scopus:0038399975
- ISSN
- 2049-632X
- DOI
- 10.1016/S0928-8244(03)00030-0
- language
- English
- LU publication?
- yes
- id
- 99056e6e-a2dc-4c1e-b976-048f047cf682 (old id 310909)
- date added to LUP
- 2016-04-01 11:58:17
- date last changed
- 2022-01-26 20:55:06
@article{99056e6e-a2dc-4c1e-b976-048f047cf682, abstract = {{Antibodies to Helicobacter pylori, Chlamydia spp. and Mycobacterium bovis were determined in patients with coronary heart disease, H. pylori-related dyspepsia, and tuberculosis, and healthy controls. Enzyme-linked immunosorbent assay was conducted with a glycine extract and CagA protein of H. pylori, chlamydial lipopolysaccharide and mycobacterial heat shock protein Hsp65. The prevalence of anti-glycine extract IgG in coronary heart disease patients was higher than in the tuberculosis group and controls, and the same as in dyspeptic patients. Anti-chlamydial IgG were more prevalent in the coronary heart disease group than in healthy subjects. There was no difference in the prevalence of anti-CagA IgG in the coronary heart disease group and controls or anti-Hsp65 IgG in the patients with coronary heart disease, dyspepsia, tuberculosis, and controls. Anti-glycine extract IgA (like anti-glycine extract IgG) were more prevalent in the coronary heart disease group than in the healthy group. The highest anti-glycine extract IgG/IgA and anti-chlamydial IgG titers were more frequent in coronary heart disease patients as compared with controls. Infections with H. pylori and Chlamydia spp. and enhanced production of antibodies to these pathogens may predispose to human atherosclerosis. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.}}, author = {{Chmiela, Magdalena and Kowlewicz-Kulbat, Magdalena and Miszczak, Aneta and Wisniewska, Monika and Rechcinski, Tomasz and Kolodziej, Katarzyna and Kasprzak, Jaroslaw and Wadström, Torkel and Rudnicka, Wieslawa}}, issn = {{2049-632X}}, keywords = {{Helicobacter pylori; Chlamydia spp.; atherosclerosis}}, language = {{eng}}, number = {{3}}, pages = {{187--192}}, publisher = {{Wiley-Blackwell}}, series = {{Pathogens and Disease}}, title = {{A link between Helicobacter pylori and/or Chlamydia spp. infections and atherosclerosis}}, url = {{http://dx.doi.org/10.1016/S0928-8244(03)00030-0}}, doi = {{10.1016/S0928-8244(03)00030-0}}, volume = {{36}}, year = {{2003}}, }