The Expression of β-Microseminoprotein but Not CRISP3 Is Reduced in Ovarian Cancer and Correlates to Survival.
(2012) In Anticancer research 32(9). p.3993-3999- Abstract
- β-Microseminoprotein (MSMB) is an abundant protein in seminal plasma. Most of it is present as a free protein but a small part is bound to cysteine-rich secretory protein 3 (CRISP3) as a non-covalent complex. Even though their physiological function is unknown, both MSMB and CRISP3 have been ascribed roles in prostate carcinogenesis. Thus, several recent experimental studies indicate a tumor-suppressor role for MSMB. The present study was undertaken in order to evaluate, for the first time, the expression of MSMB and CRISP3 in ovaries and in ovarian tumors and to determine if their expression might indicate a role in ovarian tumor development.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3123838
- author
- Henriksen, Rudi LU ; Lundwall, Åke LU ; Udby, Lene and Fernlund, Per LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- CRISP3, beta-Microseminoprotein, immunohistochemistry, ovary, ovarian, cancer, survival
- in
- Anticancer research
- volume
- 32
- issue
- 9
- pages
- 3993 - 3999
- publisher
- International Institute of Cancer Research
- external identifiers
-
- wos:000309243200053
- pmid:22993349
- scopus:84866990034
- ISSN
- 1791-7530
- language
- English
- LU publication?
- yes
- id
- 9a9597f1-ab7f-4dd4-b296-132009c1b73a (old id 3123838)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22993349?dopt=Abstract
- date added to LUP
- 2016-04-01 10:46:55
- date last changed
- 2022-05-13 20:16:18
@article{9a9597f1-ab7f-4dd4-b296-132009c1b73a, abstract = {{β-Microseminoprotein (MSMB) is an abundant protein in seminal plasma. Most of it is present as a free protein but a small part is bound to cysteine-rich secretory protein 3 (CRISP3) as a non-covalent complex. Even though their physiological function is unknown, both MSMB and CRISP3 have been ascribed roles in prostate carcinogenesis. Thus, several recent experimental studies indicate a tumor-suppressor role for MSMB. The present study was undertaken in order to evaluate, for the first time, the expression of MSMB and CRISP3 in ovaries and in ovarian tumors and to determine if their expression might indicate a role in ovarian tumor development.}}, author = {{Henriksen, Rudi and Lundwall, Åke and Udby, Lene and Fernlund, Per}}, issn = {{1791-7530}}, keywords = {{CRISP3; beta-Microseminoprotein; immunohistochemistry; ovary; ovarian; cancer; survival}}, language = {{eng}}, number = {{9}}, pages = {{3993--3999}}, publisher = {{International Institute of Cancer Research}}, series = {{Anticancer research}}, title = {{The Expression of β-Microseminoprotein but Not CRISP3 Is Reduced in Ovarian Cancer and Correlates to Survival.}}, url = {{http://www.ncbi.nlm.nih.gov/pubmed/22993349?dopt=Abstract}}, volume = {{32}}, year = {{2012}}, }