Evaluation of MLH1 I219V Polymorphism in Unrelated South American Individuals Suspected of Having Lynch Syndrome.
(2012) In Anticancer research 32(10). p.4347-4351- Abstract
- Some single-nucleotide polymorphisms are associated with higher risk of colorectal cancer development and are suggested to explain part of the genetic contribution to Lynch syndrome. Aim: To evaluate the mutL homolog 1 (MLH1) I219V polymorphism in 124 unrelated South American individuals suspected of having Lynch syndrome, based on frequency, association with pathogenic MLH1 and mutS homolog 2 (MSH2) mutation and clinical features.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3160802
- author
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- MLH1, I219V, MSH2, Lynch syndrome, single-nucleotide polymorphism
- in
- Anticancer research
- volume
- 32
- issue
- 10
- pages
- 4347 - 4351
- publisher
- International Institute of Cancer Research
- external identifiers
-
- wos:000310111800020
- pmid:23060557
- scopus:84867761432
- ISSN
- 1791-7530
- language
- English
- LU publication?
- yes
- id
- f862dbe9-2e3b-4efe-a5b6-250dfc90f21b (old id 3160802)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23060557?dopt=Abstract
- date added to LUP
- 2016-04-01 10:25:50
- date last changed
- 2022-01-25 23:09:21
@article{f862dbe9-2e3b-4efe-a5b6-250dfc90f21b, abstract = {{Some single-nucleotide polymorphisms are associated with higher risk of colorectal cancer development and are suggested to explain part of the genetic contribution to Lynch syndrome. Aim: To evaluate the mutL homolog 1 (MLH1) I219V polymorphism in 124 unrelated South American individuals suspected of having Lynch syndrome, based on frequency, association with pathogenic MLH1 and mutS homolog 2 (MSH2) mutation and clinical features.}}, author = {{Dominguez, Mev and DA Silva, Felipe Carneiro and Santos, Erika Maria Monteiro and DA Silva, Sabrina Daniela and DE Oliveira Ferreira, Fabio and Junior, Samuel Aguiar and Gomy, Israel and Vaccaro, Carlos and Redal, Maria Ana and Della Valle, Adriana and Sarroca, Carlos and Rasmussen, Lene and Carraro, Dirce Maria and Rossi, Benedito Mauro}}, issn = {{1791-7530}}, keywords = {{MLH1; I219V; MSH2; Lynch syndrome; single-nucleotide polymorphism}}, language = {{eng}}, number = {{10}}, pages = {{4347--4351}}, publisher = {{International Institute of Cancer Research}}, series = {{Anticancer research}}, title = {{Evaluation of MLH1 I219V Polymorphism in Unrelated South American Individuals Suspected of Having Lynch Syndrome.}}, url = {{http://www.ncbi.nlm.nih.gov/pubmed/23060557?dopt=Abstract}}, volume = {{32}}, year = {{2012}}, }