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Digital twins to personalize medicine

Björnsson, Bergthor ; Borrebaeck, Carl LU ; Elander, Nils ; Gasslander, Thomas ; Gawel, Danuta R. ; Gustafsson, Mika ; Jörnsten, Rebecka ; Lee, Eun Jung ; Li, Xinxiu and Lilja, Sandra , et al. (2019) In Genome Medicine 12.
Abstract

Personalized medicine requires the integration and processing of vast amounts of data. Here, we propose a solution to this challenge that is based on constructing Digital Twins. These are high-resolution models of individual patients that are computationally treated with thousands of drugs to find the drug that is optimal for the patient.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Genome Medicine
volume
12
article number
4
publisher
BioMed Central (BMC)
external identifiers
  • pmid:31892363
  • scopus:85077448104
ISSN
1756-994X
DOI
10.1186/s13073-019-0701-3
language
English
LU publication?
yes
id
31a5b00a-1b28-4efe-94f7-06f519a8d5e2
date added to LUP
2020-01-20 12:36:54
date last changed
2024-11-15 00:52:21
@article{31a5b00a-1b28-4efe-94f7-06f519a8d5e2,
  abstract     = {{<p>Personalized medicine requires the integration and processing of vast amounts of data. Here, we propose a solution to this challenge that is based on constructing Digital Twins. These are high-resolution models of individual patients that are computationally treated with thousands of drugs to find the drug that is optimal for the patient.</p>}},
  author       = {{Björnsson, Bergthor and Borrebaeck, Carl and Elander, Nils and Gasslander, Thomas and Gawel, Danuta R. and Gustafsson, Mika and Jörnsten, Rebecka and Lee, Eun Jung and Li, Xinxiu and Lilja, Sandra and Martínez-Enguita, David and Matussek, Andreas and Sandström, Per and Schäfer, Samuel and Stenmarker, Margaretha and Sun, X. F. and Sysoev, Oleg and Zhang, Huan and Benson, Mikael}},
  issn         = {{1756-994X}},
  language     = {{eng}},
  month        = {{12}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{Genome Medicine}},
  title        = {{Digital twins to personalize medicine}},
  url          = {{http://dx.doi.org/10.1186/s13073-019-0701-3}},
  doi          = {{10.1186/s13073-019-0701-3}},
  volume       = {{12}},
  year         = {{2019}},
}