Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Theoretical description of modern 1 H in Vivo magnetic resonance spectroscopic pulse sequences

Landheer, Karl ; Schulte, Rolf F ; Treacy, Michael S ; Swanberg, Kelley M LU orcid and Juchem, Christoph (2020) In Journal of Magnetic Resonance Imaging 51(4). p.1008-1029
Abstract

This article reviews the most commonly used modern sequences designed to confront the two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization and metabolic specificity. The purpose of this review article is to provide a deeper and clearer understanding of the underlying mechanisms by which all modern MRS sequences operate. A descriptive explanation, consistent pulse sequence diagram, and theoretical concepts of the measured signal are given for five spatial localization sequences and three modules designed to increase metabolic specificity. Cross-sequence comparisons, including potential modifications for estimating quantitative measures like spin-lattice relaxation time T1 , spin-spin relaxation time... (More)

This article reviews the most commonly used modern sequences designed to confront the two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization and metabolic specificity. The purpose of this review article is to provide a deeper and clearer understanding of the underlying mechanisms by which all modern MRS sequences operate. A descriptive explanation, consistent pulse sequence diagram, and theoretical concepts of the measured signal are given for five spatial localization sequences and three modules designed to increase metabolic specificity. Cross-sequence comparisons, including potential modifications for estimating quantitative measures like spin-lattice relaxation time T1 , spin-spin relaxation time T2 , and diffusion coefficients are briefly discussed. Level of Evidence: 5 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2020;51:1008-1029.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
Diffusion Magnetic Resonance Imaging, Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy
in
Journal of Magnetic Resonance Imaging
volume
51
issue
4
pages
1008 - 1029
publisher
John Wiley & Sons Inc.
external identifiers
  • scopus:85068507308
  • pmid:31273880
ISSN
1522-2586
DOI
10.1002/jmri.26846
language
English
LU publication?
no
additional info
© 2019 International Society for Magnetic Resonance in Medicine.
id
31d9eda9-dd8e-4742-8618-1e4d4e6909e0
date added to LUP
2023-09-18 15:02:05
date last changed
2024-06-15 08:50:05
@article{31d9eda9-dd8e-4742-8618-1e4d4e6909e0,
  abstract     = {{<p>This article reviews the most commonly used modern sequences designed to confront the two major challenges of in vivo magnetic resonance spectroscopy (MRS): spatial localization and metabolic specificity. The purpose of this review article is to provide a deeper and clearer understanding of the underlying mechanisms by which all modern MRS sequences operate. A descriptive explanation, consistent pulse sequence diagram, and theoretical concepts of the measured signal are given for five spatial localization sequences and three modules designed to increase metabolic specificity. Cross-sequence comparisons, including potential modifications for estimating quantitative measures like spin-lattice relaxation time T1 , spin-spin relaxation time T2 , and diffusion coefficients are briefly discussed. Level of Evidence: 5 Technical Efficacy Stage: 1 J. Magn. Reson. Imaging 2020;51:1008-1029.</p>}},
  author       = {{Landheer, Karl and Schulte, Rolf F and Treacy, Michael S and Swanberg, Kelley M and Juchem, Christoph}},
  issn         = {{1522-2586}},
  keywords     = {{Diffusion Magnetic Resonance Imaging; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{1008--1029}},
  publisher    = {{John Wiley & Sons Inc.}},
  series       = {{Journal of Magnetic Resonance Imaging}},
  title        = {{Theoretical description of modern 1 H in Vivo magnetic resonance spectroscopic pulse sequences}},
  url          = {{http://dx.doi.org/10.1002/jmri.26846}},
  doi          = {{10.1002/jmri.26846}},
  volume       = {{51}},
  year         = {{2020}},
}