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Comparability of 12-lead ECGs derived from EASI leads with standard 12-lead ECGs in the classification of acute myocardial ischemia and old myocardial infarction

Rautaharju, PM; Zhou, SH; Hancock, EW; Horacek, BM; Feild, DQ; Lindauer, JM; Wagner, GS; Pahlm, Olle LU and Feldman, CL (2002) In Journal of Electrocardiology 35(4, part 2). p.35-39
Abstract
We compared 12-lead electrocardiograms (ECGs) derived with an improved transformation matrix from EASI leads and standard 12-lead ECGs in the detection of acute myocardial ischemia and old infarction (MI). For the ischemia test, we used ECGs of 40 patients recorded prior to and at peak inflation during percutaneous transluminal coronary angioplasty, and for old MI we used test ECGs of 382 non-MI subjects and of 472 patients with prior MI documented by enzyme findings. Two experienced ECG readers served as separate, independent standards for lead-set comparisons, and the Philips ECG analysis program also classified the ECGs. The results showed no significant differences between the two lead sets in the detection of acute inflation-induced... (More)
We compared 12-lead electrocardiograms (ECGs) derived with an improved transformation matrix from EASI leads and standard 12-lead ECGs in the detection of acute myocardial ischemia and old infarction (MI). For the ischemia test, we used ECGs of 40 patients recorded prior to and at peak inflation during percutaneous transluminal coronary angioplasty, and for old MI we used test ECGs of 382 non-MI subjects and of 472 patients with prior MI documented by enzyme findings. Two experienced ECG readers served as separate, independent standards for lead-set comparisons, and the Philips ECG analysis program also classified the ECGs. The results showed no significant differences between the two lead sets in the detection of acute inflation-induced ischemia or of old MI according to coding by the electrocardiographers or the computer program. No significant differences were found between the electrocardiographers and the lead sets for acute ischemia. Classification differences between the electrocardiographers were larger than those between the lead sets for acute and old MI and were significant for the latter (P <.001). A more detailed comparison of the lead sets suggested a possible need for modified old-MI criteria and optimization of ST classification thresholds for acute ischemic injury, specific for the EASI 12-lead ECG. We conclude that the EASI-derived 12-lead ECG deserves serious consideration as an alternative to the standard 12-lead ECG in emergency situations and for monitoring in acute-care setting. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
myocardial ischemia, electrocardiogram, EAST lead ECG, infarction, myocardial
in
Journal of Electrocardiology
volume
35
issue
4, part 2
pages
35 - 39
publisher
Elsevier
external identifiers
  • wos:000180263200005
  • pmid:12539097
  • scopus:0036938984
ISSN
1532-8430
DOI
10.1054/jelc.2002.37152
language
English
LU publication?
yes
id
c524a891-6d31-48a9-914d-a91a868e6ab2 (old id 320322)
date added to LUP
2007-11-09 14:20:43
date last changed
2017-04-02 03:37:41
@article{c524a891-6d31-48a9-914d-a91a868e6ab2,
  abstract     = {We compared 12-lead electrocardiograms (ECGs) derived with an improved transformation matrix from EASI leads and standard 12-lead ECGs in the detection of acute myocardial ischemia and old infarction (MI). For the ischemia test, we used ECGs of 40 patients recorded prior to and at peak inflation during percutaneous transluminal coronary angioplasty, and for old MI we used test ECGs of 382 non-MI subjects and of 472 patients with prior MI documented by enzyme findings. Two experienced ECG readers served as separate, independent standards for lead-set comparisons, and the Philips ECG analysis program also classified the ECGs. The results showed no significant differences between the two lead sets in the detection of acute inflation-induced ischemia or of old MI according to coding by the electrocardiographers or the computer program. No significant differences were found between the electrocardiographers and the lead sets for acute ischemia. Classification differences between the electrocardiographers were larger than those between the lead sets for acute and old MI and were significant for the latter (P &lt;.001). A more detailed comparison of the lead sets suggested a possible need for modified old-MI criteria and optimization of ST classification thresholds for acute ischemic injury, specific for the EASI 12-lead ECG. We conclude that the EASI-derived 12-lead ECG deserves serious consideration as an alternative to the standard 12-lead ECG in emergency situations and for monitoring in acute-care setting.},
  author       = {Rautaharju, PM and Zhou, SH and Hancock, EW and Horacek, BM and Feild, DQ and Lindauer, JM and Wagner, GS and Pahlm, Olle and Feldman, CL},
  issn         = {1532-8430},
  keyword      = {myocardial ischemia,electrocardiogram,EAST lead ECG,infarction,myocardial},
  language     = {eng},
  number       = {4, part 2},
  pages        = {35--39},
  publisher    = {Elsevier},
  series       = {Journal of Electrocardiology},
  title        = {Comparability of 12-lead ECGs derived from EASI leads with standard 12-lead ECGs in the classification of acute myocardial ischemia and old myocardial infarction},
  url          = {http://dx.doi.org/10.1054/jelc.2002.37152},
  volume       = {35},
  year         = {2002},
}