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Acne vulgaris - A disease of western civilization

Cordain, L; Lindeberg, Staffan LU ; Hurtado, M; Hill, K; Eaton, SB and Brand-Miller, J (2002) In Archives of Dermatology 138(12). p.1584-1590
Abstract
Background: In westernized societies, acne vulgaris is a nearly universal skin disease afflicting 79% to 95% of the adolescent population. In men and women older than 25 years, 40% to 54% have some degree of facial acne, and clinical facial acne persists into middle age in 12% of women and 3% of men. Epidemiological evidence suggests that acne incidence rates are considerably lower in nonwesternized societies. Herein we report the prevalence of acne in 2 nonwesternized populations: the Kitavan Islanders of Papua New Guinea and the Ache hunter-gatherers of Paraguay. Additionally, we analyze how elements in nonwesternized environments may influence the development of acne. Observations: Of 1200 Kitavan subjects examined (including 300 aged... (More)
Background: In westernized societies, acne vulgaris is a nearly universal skin disease afflicting 79% to 95% of the adolescent population. In men and women older than 25 years, 40% to 54% have some degree of facial acne, and clinical facial acne persists into middle age in 12% of women and 3% of men. Epidemiological evidence suggests that acne incidence rates are considerably lower in nonwesternized societies. Herein we report the prevalence of acne in 2 nonwesternized populations: the Kitavan Islanders of Papua New Guinea and the Ache hunter-gatherers of Paraguay. Additionally, we analyze how elements in nonwesternized environments may influence the development of acne. Observations: Of 1200 Kitavan subjects examined (including 300 aged 15-25 years), no case of acne (grade I with multiple comedones or grades 2-4) was observed. Of 115 Ache subjects examined (including 15 aged 15-25 years) over 843 days, no case of active acne (grades 1-4) was observed. Conclusions: The astonishing difference in acne incidence rates between nonwesternized and fully modernized societies cannot be solely attributed to genetic differences among populations but likely results from differing environmental factors. identification of these factors may be useful in the treatment of acne in Western populations. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Archives of Dermatology
volume
138
issue
12
pages
1584 - 1590
publisher
American Medical Association
external identifiers
  • pmid:12472346
  • wos:000179804700007
  • scopus:0036900817
ISSN
0003-987X
DOI
10.1001/archderm.138.12.1584
language
English
LU publication?
yes
id
99da6f2b-38d7-4d52-92f0-708941862c4b (old id 322093)
date added to LUP
2007-08-02 14:38:24
date last changed
2017-12-10 04:32:30
@article{99da6f2b-38d7-4d52-92f0-708941862c4b,
  abstract     = {Background: In westernized societies, acne vulgaris is a nearly universal skin disease afflicting 79% to 95% of the adolescent population. In men and women older than 25 years, 40% to 54% have some degree of facial acne, and clinical facial acne persists into middle age in 12% of women and 3% of men. Epidemiological evidence suggests that acne incidence rates are considerably lower in nonwesternized societies. Herein we report the prevalence of acne in 2 nonwesternized populations: the Kitavan Islanders of Papua New Guinea and the Ache hunter-gatherers of Paraguay. Additionally, we analyze how elements in nonwesternized environments may influence the development of acne. Observations: Of 1200 Kitavan subjects examined (including 300 aged 15-25 years), no case of acne (grade I with multiple comedones or grades 2-4) was observed. Of 115 Ache subjects examined (including 15 aged 15-25 years) over 843 days, no case of active acne (grades 1-4) was observed. Conclusions: The astonishing difference in acne incidence rates between nonwesternized and fully modernized societies cannot be solely attributed to genetic differences among populations but likely results from differing environmental factors. identification of these factors may be useful in the treatment of acne in Western populations.},
  author       = {Cordain, L and Lindeberg, Staffan and Hurtado, M and Hill, K and Eaton, SB and Brand-Miller, J},
  issn         = {0003-987X},
  language     = {eng},
  number       = {12},
  pages        = {1584--1590},
  publisher    = {American Medical Association},
  series       = {Archives of Dermatology},
  title        = {Acne vulgaris - A disease of western civilization},
  url          = {http://dx.doi.org/10.1001/archderm.138.12.1584},
  volume       = {138},
  year         = {2002},
}