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Orientational correlations in confined DNA

Werner, E.; Persson, F.; Westerlund, F.; Tegenfeldt, Jonas LU and Mehlig, B. (2012) In Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)2001-01-01+01:002016-01-01+01:00 86(4). p.041802-041802
Abstract
We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)2001-01-01+01:002016-01-01+01:00
volume
86
issue
4
pages
041802 - 041802
publisher
American Physical Society
external identifiers
  • wos:000309731700005
  • scopus:84867533563
ISSN
1539-3755
DOI
10.1103/PhysRevE.86.041802
language
English
LU publication?
yes
id
397ff7d1-776f-4454-a896-b01fff0d0540 (old id 3224875)
date added to LUP
2012-12-12 09:26:16
date last changed
2017-02-19 03:03:52
@article{397ff7d1-776f-4454-a896-b01fff0d0540,
  abstract     = {We study how the orientational correlations of DNA confined to nanochannels depend on the channel diameter D by means of Monte Carlo simulations and a mean-field theory. This theory describes DNA conformations in the experimentally relevant regime where the Flory-de Gennes theory does not apply. We show how local correlations determine the dependence of the end-to-end distance of the DNA molecule upon D. Tapered nanochannels provide the necessary resolution in D to study experimentally how the extension of confined DNA molecules depends upon D. Our experimental and theoretical results are in qualitative agreement.},
  author       = {Werner, E. and Persson, F. and Westerlund, F. and Tegenfeldt, Jonas and Mehlig, B.},
  issn         = {1539-3755},
  language     = {eng},
  number       = {4},
  pages        = {041802--041802},
  publisher    = {American Physical Society},
  series       = {Physical Review E (Statistical, Nonlinear, and Soft Matter Physics)2001-01-01+01:002016-01-01+01:00},
  title        = {Orientational correlations in confined DNA},
  url          = {http://dx.doi.org/10.1103/PhysRevE.86.041802},
  volume       = {86},
  year         = {2012},
}