On the behavior of prolate spheroids in a standing surface acoustic wave field
(2023) In Microfluidics and Nanofluidics 27(12).- Abstract
The active manipulation of particle and cell trajectories in fluids by high-frequency standing surface acoustic waves (sSAW) allows to separate particles and cells systematically depending on their size and acoustic contrast. However, process technologies and biomedical applications usually operate with non-spherical particles, for which the prediction of acoustic forces is highly challenging and remains a subject of ongoing research. In this study, the dynamical behavior of prolate spheroids exposed to a three-dimensional acoustic field with multiple pressure nodes along the channel width is examined. Optical measurements reveal an alignment of the particles orthogonal to the pressure nodes of the sSAW, which has not been reported in... (More)
The active manipulation of particle and cell trajectories in fluids by high-frequency standing surface acoustic waves (sSAW) allows to separate particles and cells systematically depending on their size and acoustic contrast. However, process technologies and biomedical applications usually operate with non-spherical particles, for which the prediction of acoustic forces is highly challenging and remains a subject of ongoing research. In this study, the dynamical behavior of prolate spheroids exposed to a three-dimensional acoustic field with multiple pressure nodes along the channel width is examined. Optical measurements reveal an alignment of the particles orthogonal to the pressure nodes of the sSAW, which has not been reported in literature so far. The dynamical behavior of the particles is analyzed under controlled initial conditions for various motion patterns by imposing a phase shift on the sSAW. To gain detailed understanding of the particle dynamics, a three-dimensional numerical model is developed to predict the acoustic force and torque acting on a prolate spheroid. Considering the acoustically induced streaming around the particle, the numerical results are in excellent agreement with experimental findings. Using the proposed numerical model, a dependence of the acoustic force on the particle shape is found in relation to the acoustic impedance of the channel ceiling. Hence, the numerical model presented herein promises high progress for the design of separation devices utilizing sSAW, exploiting an additional separation criterion based on the particle shape.
(Less)
- author
- Sachs, Sebastian ; Schmidt, Hagen ; Cierpka, Christian LU and König, Jörg
- organization
- publishing date
- 2023-12
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Acoustofluidics, Non-spherical particle, Numerical simulation, Particle separation, SAW, Surface acoustic wave
- in
- Microfluidics and Nanofluidics
- volume
- 27
- issue
- 12
- article number
- 81
- publisher
- Springer
- external identifiers
-
- scopus:85174604599
- ISSN
- 1613-4982
- DOI
- 10.1007/s10404-023-02690-z
- language
- English
- LU publication?
- yes
- id
- 3239a187-1959-4e3f-8605-dd6ce7ba4b53
- date added to LUP
- 2024-01-11 15:30:53
- date last changed
- 2024-01-11 15:32:33
@article{3239a187-1959-4e3f-8605-dd6ce7ba4b53,
abstract = {{<p>The active manipulation of particle and cell trajectories in fluids by high-frequency standing surface acoustic waves (sSAW) allows to separate particles and cells systematically depending on their size and acoustic contrast. However, process technologies and biomedical applications usually operate with non-spherical particles, for which the prediction of acoustic forces is highly challenging and remains a subject of ongoing research. In this study, the dynamical behavior of prolate spheroids exposed to a three-dimensional acoustic field with multiple pressure nodes along the channel width is examined. Optical measurements reveal an alignment of the particles orthogonal to the pressure nodes of the sSAW, which has not been reported in literature so far. The dynamical behavior of the particles is analyzed under controlled initial conditions for various motion patterns by imposing a phase shift on the sSAW. To gain detailed understanding of the particle dynamics, a three-dimensional numerical model is developed to predict the acoustic force and torque acting on a prolate spheroid. Considering the acoustically induced streaming around the particle, the numerical results are in excellent agreement with experimental findings. Using the proposed numerical model, a dependence of the acoustic force on the particle shape is found in relation to the acoustic impedance of the channel ceiling. Hence, the numerical model presented herein promises high progress for the design of separation devices utilizing sSAW, exploiting an additional separation criterion based on the particle shape.</p>}},
author = {{Sachs, Sebastian and Schmidt, Hagen and Cierpka, Christian and König, Jörg}},
issn = {{1613-4982}},
keywords = {{Acoustofluidics; Non-spherical particle; Numerical simulation; Particle separation; SAW; Surface acoustic wave}},
language = {{eng}},
number = {{12}},
publisher = {{Springer}},
series = {{Microfluidics and Nanofluidics}},
title = {{On the behavior of prolate spheroids in a standing surface acoustic wave field}},
url = {{http://dx.doi.org/10.1007/s10404-023-02690-z}},
doi = {{10.1007/s10404-023-02690-z}},
volume = {{27}},
year = {{2023}},
}