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Biopsy sampling requirements for the estimation of muscle capillarization

Porter, MM; Koolage, CW and Lexell, Jan LU (2002) In Muscle and Nerve 26(4). p.546-548
Abstract
The aim of this study was to determine the number of tibialis anterior biopsy samples and muscle fibers required to estimate the capillary supply of individual muscle fibers (C:F-i). C:F-i was calculated for 25 type 1 fibers in each of 8 images from 3 biopsies of 5 young healthy individuals. Sequential estimation analysis indicated that 50 fibers from one biopsy are sufficient to characterize the C:F-i of the tibialis anterior for a group of subjects. Thus, when analyzing the capillarization of the tibialis anterior, the requirements of only one biopsy sample and 50 fibers means a great reduction in time for analysis and in the invasiveness of the procedure. (C) 2002 Wiley Periodicals, Inc.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
biopsy methods, capillaries, skeletal, muscle
in
Muscle and Nerve
volume
26
issue
4
pages
546 - 548
publisher
John Wiley & Sons
external identifiers
  • pmid:12362422
  • wos:000178385500015
  • scopus:0036788647
ISSN
0148-639X
DOI
10.1002/mus.10221
language
English
LU publication?
yes
id
4c152628-7215-43fb-b3ee-3ac9bd21ad55 (old id 325976)
date added to LUP
2007-11-09 12:18:45
date last changed
2017-05-21 03:33:16
@article{4c152628-7215-43fb-b3ee-3ac9bd21ad55,
  abstract     = {The aim of this study was to determine the number of tibialis anterior biopsy samples and muscle fibers required to estimate the capillary supply of individual muscle fibers (C:F-i). C:F-i was calculated for 25 type 1 fibers in each of 8 images from 3 biopsies of 5 young healthy individuals. Sequential estimation analysis indicated that 50 fibers from one biopsy are sufficient to characterize the C:F-i of the tibialis anterior for a group of subjects. Thus, when analyzing the capillarization of the tibialis anterior, the requirements of only one biopsy sample and 50 fibers means a great reduction in time for analysis and in the invasiveness of the procedure. (C) 2002 Wiley Periodicals, Inc.},
  author       = {Porter, MM and Koolage, CW and Lexell, Jan},
  issn         = {0148-639X},
  keyword      = {biopsy methods,capillaries,skeletal,muscle},
  language     = {eng},
  number       = {4},
  pages        = {546--548},
  publisher    = {John Wiley & Sons},
  series       = {Muscle and Nerve},
  title        = {Biopsy sampling requirements for the estimation of muscle capillarization},
  url          = {http://dx.doi.org/10.1002/mus.10221},
  volume       = {26},
  year         = {2002},
}