Hydrolytically active tetranuclear nickel complexes with structural resemblance to the active site of urease
(2002) In Inorganic Chemistry 41(20). p.4981-4983- Abstract
- Reaction of the new asymmetric ligand 2-(N-isopropyl-N-((1-methylimidazolyl)methyl)aminomethyl)-6-(N-carboxylm ethyl-N-((1-methylimidazolyl)methyl) aminomethyl)-4-methylphenol (ICIMP) with nickel perchlorate and diphenylacetic acid leads to the formation of tetranuclear nickel complexes, whose crystal structures reveal that they consist of dimers of dimers in which each Ni-2 unit has a coordination environment that is similar to the active site of urease. One complex has been shown to coordinate urea and catalyze the hydrolysis of an organophosphate monoester.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/326160
- author
- Carlsson, Håkan LU ; Haukka, Matti and Nordlander, Ebbe LU
- organization
- publishing date
- 2002
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Inorganic Chemistry
- volume
- 41
- issue
- 20
- pages
- 4981 - 4983
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- pmid:12354025
- wos:000178422600003
- scopus:0037037523
- ISSN
- 1520-510X
- DOI
- 10.1021/ic025839p
- language
- English
- LU publication?
- yes
- id
- bd0431b1-a638-4401-8413-cbeb7a4875f2 (old id 326160)
- date added to LUP
- 2016-04-01 12:03:45
- date last changed
- 2022-04-29 00:06:58
@article{bd0431b1-a638-4401-8413-cbeb7a4875f2, abstract = {{Reaction of the new asymmetric ligand 2-(N-isopropyl-N-((1-methylimidazolyl)methyl)aminomethyl)-6-(N-carboxylm ethyl-N-((1-methylimidazolyl)methyl) aminomethyl)-4-methylphenol (ICIMP) with nickel perchlorate and diphenylacetic acid leads to the formation of tetranuclear nickel complexes, whose crystal structures reveal that they consist of dimers of dimers in which each Ni-2 unit has a coordination environment that is similar to the active site of urease. One complex has been shown to coordinate urea and catalyze the hydrolysis of an organophosphate monoester.}}, author = {{Carlsson, Håkan and Haukka, Matti and Nordlander, Ebbe}}, issn = {{1520-510X}}, language = {{eng}}, number = {{20}}, pages = {{4981--4983}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Inorganic Chemistry}}, title = {{Hydrolytically active tetranuclear nickel complexes with structural resemblance to the active site of urease}}, url = {{http://dx.doi.org/10.1021/ic025839p}}, doi = {{10.1021/ic025839p}}, volume = {{41}}, year = {{2002}}, }