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Hydrolytically active tetranuclear nickel complexes with structural resemblance to the active site of urease

Carlsson, Håkan LU ; Haukka, Matti and Nordlander, Ebbe LU (2002) In Inorganic Chemistry 41(20). p.4981-4983
Abstract
Reaction of the new asymmetric ligand 2-(N-isopropyl-N-((1-methylimidazolyl)methyl)aminomethyl)-6-(N-carboxylm ethyl-N-((1-methylimidazolyl)methyl) aminomethyl)-4-methylphenol (ICIMP) with nickel perchlorate and diphenylacetic acid leads to the formation of tetranuclear nickel complexes, whose crystal structures reveal that they consist of dimers of dimers in which each Ni-2 unit has a coordination environment that is similar to the active site of urease. One complex has been shown to coordinate urea and catalyze the hydrolysis of an organophosphate monoester.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Inorganic Chemistry
volume
41
issue
20
pages
4981 - 4983
publisher
The American Chemical Society
external identifiers
  • pmid:12354025
  • wos:000178422600003
  • scopus:0037037523
ISSN
1520-510X
DOI
10.1021/ic025839p
language
English
LU publication?
yes
id
bd0431b1-a638-4401-8413-cbeb7a4875f2 (old id 326160)
date added to LUP
2007-08-13 14:13:26
date last changed
2017-01-01 04:48:00
@article{bd0431b1-a638-4401-8413-cbeb7a4875f2,
  abstract     = {Reaction of the new asymmetric ligand 2-(N-isopropyl-N-((1-methylimidazolyl)methyl)aminomethyl)-6-(N-carboxylm ethyl-N-((1-methylimidazolyl)methyl) aminomethyl)-4-methylphenol (ICIMP) with nickel perchlorate and diphenylacetic acid leads to the formation of tetranuclear nickel complexes, whose crystal structures reveal that they consist of dimers of dimers in which each Ni-2 unit has a coordination environment that is similar to the active site of urease. One complex has been shown to coordinate urea and catalyze the hydrolysis of an organophosphate monoester.},
  author       = {Carlsson, Håkan and Haukka, Matti and Nordlander, Ebbe},
  issn         = {1520-510X},
  language     = {eng},
  number       = {20},
  pages        = {4981--4983},
  publisher    = {The American Chemical Society},
  series       = {Inorganic Chemistry},
  title        = {Hydrolytically active tetranuclear nickel complexes with structural resemblance to the active site of urease},
  url          = {http://dx.doi.org/10.1021/ic025839p},
  volume       = {41},
  year         = {2002},
}