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Measuring early vascular aging in youth : An expert consensus document from the Youth Vascular Consortium

Hersant, Jeanne ; Kruger, Ruan ; Bianchini, Elisabetta ; Königstein, Karsten ; Sinha, Manish D ; Hidvégi, Erzsébet V ; Kodithuwakku, Vimarsha ; Mill, José Geraldo ; Diaz, Alejandro and Zócalo, Yanina , et al. (2025) In Journal of Hypertension
Abstract

Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and... (More)

Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and to discuss challenges in translating these methods into clinical practice.

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Please use this url to cite or link to this publication:
@article{3315e992-87de-42c8-9a34-9e051988f3a7,
  abstract     = {{<p>Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and to discuss challenges in translating these methods into clinical practice.</p>}},
  author       = {{Hersant, Jeanne and Kruger, Ruan and Bianchini, Elisabetta and Königstein, Karsten and Sinha, Manish D and Hidvégi, Erzsébet V and Kodithuwakku, Vimarsha and Mill, José Geraldo and Diaz, Alejandro and Zócalo, Yanina and Bia, Daniel and Celermajer, David and Hanssen, Henner and Johansson, Madeleine and Pucci, Giacomo and Litwin, Mieczysław and Stone, Keeron and Pugh, Christopher J A and Stoner, Lee and Urbina, Elaine M and Bruno, Rosa Maria and Nilsson, Peter M and Climie, Rachel E}},
  issn         = {{1473-5598}},
  language     = {{eng}},
  month        = {{05}},
  publisher    = {{Lippincott Williams & Wilkins}},
  series       = {{Journal of Hypertension}},
  title        = {{Measuring early vascular aging in youth : An expert consensus document from the Youth Vascular Consortium}},
  url          = {{http://dx.doi.org/10.1097/HJH.0000000000004039}},
  doi          = {{10.1097/HJH.0000000000004039}},
  year         = {{2025}},
}