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The 3D Value Framework for Sustainable Access to Effective Antibiotics

Herlitz, Anders LU ; Malmqvist, Erik and Munthe, Christian (2025) In Health Care Analysis
Abstract
Sustainable access to effective antibiotics is a main rationale for addressing antimicrobial resistance, for calls to enhance antibiotic supply security and for development support to promote health system capacity in low- and middle-income settings. Standard models for valuing pharmaceuticals fail to capture the full value of sustainable access to effective antibiotics. In effect, assessments of societal or corporate investments to promote such access underestimate their value and the cost of foregoing them. In effect, measures that could address existing sustainability problems in antibiotic supply systems are hampered. We review the features needed to avoid these problems and assess suggestions to address the flaws of existing... (More)
Sustainable access to effective antibiotics is a main rationale for addressing antimicrobial resistance, for calls to enhance antibiotic supply security and for development support to promote health system capacity in low- and middle-income settings. Standard models for valuing pharmaceuticals fail to capture the full value of sustainable access to effective antibiotics. In effect, assessments of societal or corporate investments to promote such access underestimate their value and the cost of foregoing them. In effect, measures that could address existing sustainability problems in antibiotic supply systems are hampered. We review the features needed to avoid these problems and assess suggestions to address the flaws of existing approaches, such as the STEDI-model. On this basis, we propose the 3D Value Framework, a straightforward and comprehensive model that focusses directly on what types of valuable outcomes there can be related to having sustainable access to effective antibiotics. We also sketch how this model can be used in cost-effectiveness analysis grounding public decision-making and discuss further applications in other settings. (Less)
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Antibiotics, Antimicrobial resistance, Cost-effectiveness analysis, Healthcare access, Health policy, Sustainability, Value
in
Health Care Analysis
pages
20 pages
publisher
Springer
external identifiers
  • scopus:105024242251
  • pmid:41351727
ISSN
1573-3394
DOI
10.1007/s10728-025-00552-z
language
English
LU publication?
yes
id
334d85d3-41f0-41b9-9d52-f029916dc172
date added to LUP
2026-01-05 18:09:15
date last changed
2026-01-09 03:00:06
@article{334d85d3-41f0-41b9-9d52-f029916dc172,
  abstract     = {{Sustainable access to effective antibiotics is a main rationale for addressing antimicrobial resistance, for calls to enhance antibiotic supply security and for development support to promote health system capacity in low- and middle-income settings. Standard models for valuing pharmaceuticals fail to capture the full value of sustainable access to effective antibiotics. In effect, assessments of societal or corporate investments to promote such access underestimate their value and the cost of foregoing them. In effect, measures that could address existing sustainability problems in antibiotic supply systems are hampered. We review the features needed to avoid these problems and assess suggestions to address the flaws of existing approaches, such as the STEDI-model. On this basis, we propose the 3D Value Framework, a straightforward and comprehensive model that focusses directly on what types of valuable outcomes there can be related to having sustainable access to effective antibiotics. We also sketch how this model can be used in cost-effectiveness analysis grounding public decision-making and discuss further applications in other settings.}},
  author       = {{Herlitz, Anders and Malmqvist, Erik and Munthe, Christian}},
  issn         = {{1573-3394}},
  keywords     = {{Antibiotics; Antimicrobial resistance; Cost-effectiveness analysis; Healthcare access; Health policy; Sustainability; Value}},
  language     = {{eng}},
  publisher    = {{Springer}},
  series       = {{Health Care Analysis}},
  title        = {{The 3D Value Framework for Sustainable Access to Effective Antibiotics}},
  url          = {{http://dx.doi.org/10.1007/s10728-025-00552-z}},
  doi          = {{10.1007/s10728-025-00552-z}},
  year         = {{2025}},
}